Assessing Carotid Artery Stenosis with Advanced Imaging Techniques
Perioperative Risk and Clinical Efficacy Study of Cervical Artery Stenosis Patients Through the Integration of Multimodal Imaging and Computational Fluid Dynamics
This study is testing new imaging techniques to see how well different surgeries for carotid artery narrowing can improve blood flow and quality of life for patients at risk of stroke.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 40 (estimated) |
| Ages | 18 Years to 80 Years |
| Sex | All |
| Sponsor | Sichuan Provincial People's Hospital Academic / other |
| Locations | 1 site (Chengdu, Sichuan) |
| Trial ID | NCT06294496 on ClinicalTrials.gov |
What this trial studies
This project focuses on understanding carotid artery stenosis, a significant risk factor for ischemic stroke, by collecting multimodal imaging data such as CT perfusion and angiography. It aims to create 3D models of the stenosis and analyze hemodynamics using computational fluid dynamics and artificial intelligence. The study seeks to evaluate the effects of surgical interventions, carotid endarterectomy (CEA) and carotid artery stenting (CAS), on patient outcomes and quality of life. By monitoring blood flow and oxygen levels, the research aims to tailor surgical approaches for improved results.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals clinically diagnosed with carotid stenosis.
Not a fit: Patients with vascular malformations, aneurysms, or severe heart, liver, or kidney disease may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to more personalized surgical treatments for carotid artery stenosis, enhancing patient outcomes and quality of life.
How similar studies have performed: While the integration of multimodal imaging and computational fluid dynamics is a novel approach, similar studies have shown promise in improving surgical outcomes for vascular conditions.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1) Clinical diagnosis of carotid stenosis. Exclusion Criteria: 1. Vascular stenosis with vascular malformations. 2. Aneurysm. 3. Severe heart, liver, or kidney disease.
Where this trial is running
Chengdu, Sichuan
- Sichuan Provincial People's Hospital — Chengdu, Sichuan, China (Recruiting)
Study contacts
- Principal investigator: Chunling Li, MD — Sichuan Provincial People's Hospital
- Study coordinator: Lei Guo, Master
- Email: guoleii2021@hotmail.com
- Phone: +86 15760551392
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.