Assessing Brain Responses to Sensory Stimuli in Fibromyalgia
Analysis of Brain Responses and Habituation to Multimodal Sensory Stimuli in Patients with Fibromyalgia
This study is testing how people with fibromyalgia respond to different sensory experiences to see if their brains react differently than those without the condition.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 30 (estimated) |
| Ages | 18 Years to 70 Years |
| Sex | All |
| Sponsor | National Council of Scientific and Technical Research, Argentina Government |
| Locations | 1 site (Oro Verde, Entre Ríos) |
| Trial ID | NCT06905171 on ClinicalTrials.gov |
What this trial studies
This observational study aims to evaluate event-related potentials (ERPs) and habituation in patients diagnosed with fibromyalgia. Participants will be exposed to various sensory stimuli, including auditory, visual, and somatosensory inputs, to determine if there are measurable differences in sensory responses compared to healthy controls. The study seeks to provide evidence for the hypersensitivity claims often reported by fibromyalgia patients by analyzing how their brain responses change with repeated stimuli. The findings could enhance understanding of sensory processing in fibromyalgia and inform future treatment approaches.
Who should consider this trial
Good fit: Ideal candidates include individuals diagnosed with fibromyalgia who meet specific inclusion criteria and have normal sensory function.
Not a fit: Patients with severe comorbid conditions causing more pain than fibromyalgia or those with a history of addictive behavior may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved diagnostic tools and treatment strategies for patients with fibromyalgia.
How similar studies have performed: Previous studies have shown differences in sensory processing in fibromyalgia patients, indicating that this approach has potential for meaningful insights.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: Fibromyalgia patients: * Primary diagnosis of fibromyalgia according to the criteria used by the healthcare professional in charge of the patient. * Other comorbidities are accepted as long as the pain caused by them is less severe than the pain caused by fibromyalgia. * Willingness and ability to fully understand the content and scope of the experiment and to comply with the experiment instructions. * Normal or corrected-to-normal vision. * Normal hearing Healthy controls: * No history of neurological diseases, chronic pain or musculoskeletal disorders. * Willingness and ability to fully understand the content and scope of the experiment and to comply with the experiment instructions. * Normal or corrected-to-normal vision. * Normal hearing Exclusion Criteria: Fibromyalgia patients: * Pregnancy * History of addictive behavior, defined as alcohol, cannabis, opioids or other drugs abuse. * Presence of fever, tuberculosis, malignant tumors, infectious processes, acute inflammatory processes. * Lack of cooperation Healthy controls: * Pregnancy * History of chronic pain or musculoskeletal or articular disorders * History of addictive behavior, defined as alcohol, cannabis, opioids or other drugs abuse. * Presence of fever, tuberculosis, malignant tumors, infectious processes, acute inflammatory processes. * Lack of cooperation
Where this trial is running
Oro Verde, Entre Ríos
- Faculty of Engineering-National University of Entre Ríos — Oro Verde, Entre Ríos, Argentina (Recruiting)
Study contacts
- Principal investigator: Biurrun Manresa — National Council of Scientific and Technical Research, Argentina (CONICET)
- Study coordinator: Elizabeth L Young, Bioing
- Email: elizabeth.young@uner.edu.ar
- Phone: +54(343)4975100
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.