Assessing brain oxygen levels and cognitive function after heart surgery
Cerebral Oxygenation and Neurological Functioning After Cardiac Surgery
This study is trying to see how brain oxygen levels during heart surgery affect how well patients think and remember after the surgery.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 95 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Queen's University Academic / other |
| Locations | 1 site (Kingston, Ontario) |
| Trial ID | NCT04081649 on ClinicalTrials.gov |
What this trial studies
This observational study aims to identify predictors of long-term neurological functioning in patients undergoing cardiac surgery, specifically coronary artery bypass and valvular surgery. Researchers will track patients' neurological performance before and after surgery, focusing on the relationship between intraoperative cerebral oxygenation levels and post-operative cognitive outcomes. The study utilizes near-infrared spectroscopy to measure brain oxygen levels and a robotic device called KINARM to assess neurological function. The goal is to establish a timeline of cognitive changes associated with surgical procedures.
Who should consider this trial
Good fit: Ideal candidates are adult patients scheduled for coronary artery bypass surgery or valvular surgery without pre-existing cognitive impairments.
Not a fit: Patients with pre-existing cognitive impairment or neurodegenerative conditions will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved monitoring and management strategies for cognitive outcomes in cardiac surgery patients.
How similar studies have performed: While there have been studies examining cerebral oxygenation and cognitive outcomes, this specific approach focusing on long-term neurological functioning post-cardiac surgery is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * adult patients undergoing coronary artery bypass surgery +/- valvular surgery Exclusion Criteria: * pre-existing cognitive impairment or neurodegenerative condition * any reason that participant cannot participate in follow up (lives too far away, limb amputation, speaks language other than english)
Where this trial is running
Kingston, Ontario
- Kingston General Hospital — Kingston, Ontario, Canada (Recruiting)
Study contacts
- Principal investigator: J. Gordon Boyd, MD, PhD — Queen's University
- Study coordinator: J. Gordon Boyd, MD, PhD
- Email: 2jgb1@queensu.ca
- Phone: 6135392754
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.