Assessing blood vessel function in children with type 1 diabetes and obesity
Peripheral Artery Tonometry in Children With Type 1 Diabetes and Obese Children.
This study is testing how well blood vessels work in teenagers with type 1 diabetes and obesity compared to healthy teens to see if there are any differences that could affect their heart health.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 70 (estimated) |
| Ages | 12 Years to 19 Years |
| Sex | All |
| Sponsor | Universitaire Ziekenhuizen KU Leuven Academic / other |
| Locations | 1 site (Leuven) |
| Trial ID | NCT01267591 on ClinicalTrials.gov |
What this trial studies
This observational study aims to evaluate the endothelial function in adolescents aged 12-19 years using a noninvasive method called reactive hyperemia-peripheral artery tonometry (RH-PAT). The study will compare RH-PAT scores between adolescents with type 1 diabetes and healthy controls, as well as between obese adolescents and their non-obese counterparts. By understanding the differences in vascular function, the study seeks to shed light on the cardiovascular risks associated with these conditions.
Who should consider this trial
Good fit: Ideal candidates for this study are adolescents aged 12-19 years with type 1 diabetes or obesity.
Not a fit: Patients with type 2 diabetes or obesity in the type 1 diabetes group may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to better understanding and management of cardiovascular risks in children with type 1 diabetes and obesity.
How similar studies have performed: Other studies have shown promising results in assessing endothelial function using similar noninvasive techniques, indicating potential for success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * 12-19 years of age Exclusion Criteria: * type 2 diabetes; obesity in group of type 1 diabetes
Where this trial is running
Leuven
- University Hospital Leuven — Leuven, Belgium (Recruiting)
Study contacts
- Study coordinator: kristina casteels, MD Phd
- Phone: 00-32-16-343801
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.