Assessing biomarkers to rule out coronary artery disease
Ruling Out Coronary Artery Disease and Myocardial Injury by BiOmarkers: Light'n Easy
This study is testing if certain blood markers can help doctors tell if people with suspected coronary artery disease actually have healthy arteries or not.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1000 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University Hospital, Akershus Academic / other |
| Locations | 1 site (Lørenskog) |
| Trial ID | NCT04144725 on ClinicalTrials.gov |
What this trial studies
This observational study aims to evaluate the effectiveness of cardiovascular biomarkers in identifying patients with suspected coronary artery disease (CAD) who have normal coronary vessels or no significant stenosis. It will involve 1000 patients referred for coronary computed tomography angiography (CCTA), where blood samples will be collected prior to the procedure to measure troponin levels. The study will follow patients for at least 12 months to monitor various cardiovascular outcomes, comparing biomarker levels with imaging results.
Who should consider this trial
Good fit: Ideal candidates are consenting adults over 18 years old who are referred for CCTA due to suspected coronary artery disease.
Not a fit: Patients with a short life expectancy of less than 12 months due to non-cardiovascular diseases may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could help accurately identify patients without significant coronary artery disease, potentially reducing unnecessary interventions and improving patient management.
How similar studies have performed: Other studies have shown promise in using biomarkers for diagnosing coronary artery disease, suggesting this approach may be effective.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Consenting patient over the age of 18 referred to CCTA for suspected coronary artery disease Exclusion Criteria: * Inability to provide informed consent. * Short life expectancy (\<12 months) due to non-cardiovascular disease
Where this trial is running
Lørenskog
- Akershus University Hospital — Lørenskog, Norway (Recruiting)
Study contacts
- Principal investigator: Torbjørn Omland, MD, PhD — University Hospital, Akershus
- Study coordinator: Torbjørn Omland, MD, PhD
- Email: torbjorn.omland@medisin.uio.no
- Phone: 67960000
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.