Assessing balance and vestibular function after Gammaknife treatment for vestibular schwannoma
Official title: Prospective Study : Long-term Evolution of Balance and Vestibular Function in Patients Treated With Gammaknife Radiosurgery for Vestibular Schwannoma EQUI-GAMMA
Run by University Hospital, Toulouse · NCT04859335 · Data updated 2026-11-12
This study tests how Gammaknife treatment for vestibular schwannomas affects balance and inner ear function in patients who haven't had other treatments.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 65 Years |
| Sex | All |
| Enrollment | 50 (estimated) |
| Sponsor | University Hospital, Toulouse Academic / other |
| Locations | 1 site (Toulouse) |
| Status | Recruiting |
| Started | May 21, 2021 |
| Main results expected | December 1, 2028 |
| Study ends | December 1, 2028 |
| Registry record updated | August 11, 2026 |
| Trial ID | NCT04859335 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include patients diagnosed with vestibular schwannomas who are eligible for Gammaknife radiosurgery and have not undergone previous treatments.
✕Probably not a fit
Patients with a history of prior treatment for vestibular schwannomas or those with associated otological conditions may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study evaluates the effects of Gammaknife radiosurgery on balance and vestibular function in patients with vestibular schwannomas. It aims to comprehensively assess changes in vestibular function and balance using both subjective quality of life questionnaires and objective vestibular assessments. The study focuses on patients with schwannomas smaller than 2.5-3 cm who have not received prior treatment. The results will help clarify the impact of this treatment on patients' balance and overall quality of life.
Why it matters
Potential benefit: If successful, this study could provide valuable insights into the preservation of balance and vestibular function after Gammaknife treatment, improving patient management and outcomes.
How similar studies have gone: While there have been studies on Gammaknife radiosurgery for vestibular schwannomas, comprehensive assessments of vestibular function and balance post-treatment are limited, making this approach relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Vestibular schwannoma's Patients for whom an indication of gammaknife radiosurgery was determined in a dedicated multidisciplinary consultation meeting, having not received previous treatment for this schwannoma. * Patient affiliated to Social Security * No opposition to participation Exclusion Criteria: * History of prior treatment for the presented vestibular schwannoma (surgery, fractional radiotherapy) * History of otological or otoneurological pathology associated with schwannoma * Patient with type 2 neurofibromatosis * Patient under legal protection * Pregnant or breastfeeding women
Where it's running
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CHU Toulouse
Toulouse, France Recruiting
Study contacts
- Principal investigator: Mathieu MARX, MD PhD — University Hospital, Toulouse
- Study coordinator: Mathieu MARX, MD Phd
- Email: marx.m@chu-toulouse.fr
- Phone: (+33)5 61 77 77 04
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.