Assessing and intervening on frailty in elderly gastric cancer patients undergoing surgery and chemotherapy
Frailty Assessment and Intervention in Elderly Patients with Gastric Cancer Receiving Gastrectomy and Adjuvant Chemotherapy
This study is testing ways to help older patients with advanced stomach cancer feel stronger and have better outcomes after surgery and chemotherapy.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 300 (estimated) |
| Ages | 65 Years and up |
| Sex | All |
| Sponsor | Chang Gung Memorial Hospital Academic / other |
| Drugs / interventions | chemotherapy, radiation |
| Locations | 1 site (Taoyuan, Taiwan) |
| Trial ID | NCT06055387 on ClinicalTrials.gov |
What this trial studies
This study focuses on elderly patients aged 65 and older who have locally advanced gastric cancer and are preparing for curative surgery followed by adjuvant chemotherapy. It aims to assess frailty levels in these patients and implement intervention measures to improve their outcomes. The study seeks to increase the rates of elderly patients undergoing radical surgery and receiving chemotherapy, addressing the high risk of postoperative complications and low treatment rates in this population. By enhancing the management of frailty, the study hopes to improve the overall success of treatment for these patients.
Who should consider this trial
Good fit: Ideal candidates are elderly patients aged 65 and older with locally advanced gastric cancer preparing for surgery and adjuvant chemotherapy.
Not a fit: Patients with cognitive impairment or those receiving concurrent anticancer treatments may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved surgical and chemotherapy outcomes for elderly gastric cancer patients.
How similar studies have performed: Other studies have shown success in addressing frailty in elderly patients, indicating that this approach may be beneficial.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients aged sixty-five or older with locally advanced (stage II and stage III) gastric cancer, preparing for curative gastric cancer surgery and scheduled to receive adjuvant chemotherapy within 4-8 weeks postoperatively, either as outpatients or inpatients. * Patients must provide signed informed consent. * Estimated survival of more than 3 months. * Conscious and able to communicate verbally or in writing, and willing to cooperate with invasive procedures. Exclusion Criteria: * Patients with cognitive impairment or unable to cooperate with the interventional procedures as determined by the clinical physician. * Patients receiving concurrent other anticancer treatments (radiation or surgery). * Patients with multiple types of cancer requiring simultaneous treatment.
Where this trial is running
Taoyuan, Taiwan
- Chang Gung Memorial Hospital — Taoyuan, Taiwan, Taiwan (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.