Clinical trial Recruiting at 1 site Observational Women only

Asian registry of brachytherapy for cervical cancer

Official title: Asian Gynecological Brachytherapy Registry in Cervical Cancer

Run by Tata Memorial Hospital · NCT07196033 · Data updated 2026-11-12

This project will see how different internal radiation (brachytherapy) approaches are used and perform for people in Asia with stage IB–IVA cervical cancer treated with chemoradiation.

More Stage IIIA Cervical Cancer FIGO 2018 trials

Quick facts

Study typeObservational
SexWomen only
Enrollment1000 (estimated)
SponsorTata Memorial Hospital
Government
Drugs / interventionsradiation, chemotherapy
Locations5 sites (Mumbai, Maharashtra and 4 other locations)
StatusRecruiting
StartedFebruary 20, 2026
Main results expectedMarch 15, 2028
Study endsMay 20, 2028
Registry record updatedFebruary 9, 2026
Trial IDNCT07196033 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

People with FIGO 2018 stage IB–IVA cervical cancer (squamous, adenocarcinoma, or adenosquamous histology) who were planned for definitive chemoradiation including brachytherapy are ideal candidates for inclusion.

Probably not a fit

Patients with neuroendocrine or other rare histologies, those with metastatic disease not planned for radical pelvic RT/brachytherapy, or those receiving postoperative or recurrent‑disease radiotherapy are unlikely to benefit from inclusion in this registry.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The registry uses a retrospective cohort design to collect consecutive cases from participating Asian centers over a 12‑month period, aiming for about 1,000 patients. It captures the full range of brachytherapy practice (2D to 3D), imaging modalities used for planning (X‑ray, CT, MRI, ultrasound), external beam radiation details, concurrent chemotherapy, and overall treatment time. Patient demographics, contouring practices, and institutional treatment patterns will be recorded, with monitoring and quality assurance procedures to ensure data completeness and integrity. Data handling protocols will protect privacy and a publication policy will guide multi‑institutional analysis and reporting.

Why it matters

Potential benefit: If successful, the registry could identify brachytherapy practices linked to better tumor control and fewer side effects and help centers across Asia standardize and improve care.

How similar studies have gone: Advanced brachytherapy techniques have produced strong outcomes in Europe and North America, but large multi‑centre registries documenting real‑world Asian practice are limited, so this effort is building on known techniques but filling a regional data gap.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients diagnosed with FIGO 2018 stage IB-IVA cervical cancer with squamous cell carcinoma, adenocarcinoma or adenosquamous carcinoma histological subtype.
* Planned for treatment with definitive chemo-radiation and brachytherapy. (X- ray,CT, CT-Ultrasound or MRI based).

Exclusion Criteria:

* Neuroendocrine cancer of the cervix or other rare histology subtypes.
* Patients with metastatic cervix cancer and not planned for radical doses of pelvic RT/brachytherapy may be excluded.
* Patients undergoing postoperative RT or RT for recurrent disease should be excluded.

Where it's running

  • Tata Memorial Center
    Mumbai, Maharashtra, India
    Recruiting
  • Gunma University
    Maebashi, Japan, Japan
    Not yet recruiting
  • Juntendo University
    Tokyo, Japan, Japan
    Not yet recruiting
  • Mahidol University
    Bangkok, Thailand, Thailand
    Not yet recruiting
  • Chiang Mai University
    Chiang Mai, Thailand, Thailand
    Not yet recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.