Asian registry of brachytherapy for cervical cancer
Official title: Asian Gynecological Brachytherapy Registry in Cervical Cancer
Run by Tata Memorial Hospital · NCT07196033 · Data updated 2026-11-12
This project will see how different internal radiation (brachytherapy) approaches are used and perform for people in Asia with stage IB–IVA cervical cancer treated with chemoradiation.
Quick facts
| Study type | Observational |
|---|---|
| Sex | Women only |
| Enrollment | 1000 (estimated) |
| Sponsor | Tata Memorial Hospital Government |
| Drugs / interventions | radiation, chemotherapy |
| Locations | 5 sites (Mumbai, Maharashtra and 4 other locations) |
| Status | Recruiting |
| Started | February 20, 2026 |
| Main results expected | March 15, 2028 |
| Study ends | May 20, 2028 |
| Registry record updated | February 9, 2026 |
| Trial ID | NCT07196033 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
People with FIGO 2018 stage IB–IVA cervical cancer (squamous, adenocarcinoma, or adenosquamous histology) who were planned for definitive chemoradiation including brachytherapy are ideal candidates for inclusion.
✕Probably not a fit
Patients with neuroendocrine or other rare histologies, those with metastatic disease not planned for radical pelvic RT/brachytherapy, or those receiving postoperative or recurrent‑disease radiotherapy are unlikely to benefit from inclusion in this registry.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The registry uses a retrospective cohort design to collect consecutive cases from participating Asian centers over a 12‑month period, aiming for about 1,000 patients. It captures the full range of brachytherapy practice (2D to 3D), imaging modalities used for planning (X‑ray, CT, MRI, ultrasound), external beam radiation details, concurrent chemotherapy, and overall treatment time. Patient demographics, contouring practices, and institutional treatment patterns will be recorded, with monitoring and quality assurance procedures to ensure data completeness and integrity. Data handling protocols will protect privacy and a publication policy will guide multi‑institutional analysis and reporting.
Why it matters
Potential benefit: If successful, the registry could identify brachytherapy practices linked to better tumor control and fewer side effects and help centers across Asia standardize and improve care.
How similar studies have gone: Advanced brachytherapy techniques have produced strong outcomes in Europe and North America, but large multi‑centre registries documenting real‑world Asian practice are limited, so this effort is building on known techniques but filling a regional data gap.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients diagnosed with FIGO 2018 stage IB-IVA cervical cancer with squamous cell carcinoma, adenocarcinoma or adenosquamous carcinoma histological subtype. * Planned for treatment with definitive chemo-radiation and brachytherapy. (X- ray,CT, CT-Ultrasound or MRI based). Exclusion Criteria: * Neuroendocrine cancer of the cervix or other rare histology subtypes. * Patients with metastatic cervix cancer and not planned for radical doses of pelvic RT/brachytherapy may be excluded. * Patients undergoing postoperative RT or RT for recurrent disease should be excluded.
Where it's running
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Tata Memorial Center
Mumbai, Maharashtra, India Recruiting -
Gunma University
Maebashi, Japan, Japan Not yet recruiting -
Juntendo University
Tokyo, Japan, Japan Not yet recruiting -
Mahidol University
Bangkok, Thailand, Thailand Not yet recruiting -
Chiang Mai University
Chiang Mai, Thailand, Thailand Not yet recruiting
Study contacts
- Study coordinator: Dr. Supriya Chopra
- Email: supriyasastri@gmail.com
- Phone: 9930958309
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Induction pembrolizumab with carboplatin/paclitaxel before chemoradiation and pembrolizumab maintenance for high‑risk locally advanced cervical cancer
This phase III trial tests whether giving pembrolizumab with carboplatin and paclitaxel before chemoradiation, then continuing pembrolizumab as maintenance, helps people with locally advanced high‑risk cervical cancer stay free of progression longer than starting pembrolizumab during chemoradiation.
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.