Aromatherapy inhaler to reduce distress after a hematopoietic stem cell transplant

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study provides HSCT patients with a lavender or peppermint aromatherapy inhaler on a single post-transplant day and compares distress and coping to a standard-of-care washout day. The protocol includes an initial aromatherapy day (post-transplant day +1 to +3), a washout day with only standard pharmacologic care, and a follow-up phase day (post-transplant day +3 to +5), with activities occurring on one day per phase. A three-day window for the aromatherapy phases accommodates patients' variable recovery in the immediate post-transplant period. Outcomes focus on short-term changes in distress and coping during the early post-transplant course.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Autologous and Allogeneic patients admitted to E1 for planned HSCT
* Patients with hematologic malignancies requiring HSCT
* No allergies to lavender or peppermint essential oils
* Must have received chemotherapy during preparative regimen (single or multi-agent regimen)
* Adult patient over 18 years of age
* Able to speak, read, and comprehend English
* Willing and capable of providing informed consent

Exclusion Criteria:

* Patients admitted for Chimeric Antigen Receptor T cell (CART) infusion
* Patients receiving a transplant for a germ cell tumor diagnosis
* Unexpected/unplanned admission (e.g., neutropenic fever, confusion, clinical deterioration)
* Immune effector cell-associated neurotoxicity syndrome (ICANS) grade 1 through 4
* History of scleroderma
* History of atrial fibrillation
* Known history of G6PD deficiency
* Allergic to lavender or peppermint essential oils
* Pediatric patient 18 years of age or less
* Unable to speak, read, and comprehend English
* Unwilling or incapable of providing informed consent

Where it's running

• Stanford University
  Stanford, California, United States Recruiting

Study contacts

• Principal investigator: Anna Oh, PhD, MPH, RN — Stanford University
• Study coordinator: Anna Oh, PhD, MPH, RN
• Email: aoh2@stanford.edu
• Phone: 650-512-6691

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.