Anxiety in men on active surveillance for localized prostate cancer and their partners

Quantitative and Qualitative Study of Anxiety in Patients Under Active Surveillance for Localized Prostate Cancer and Their Partners.

This project will see how much anxiety men on active surveillance for localized prostate cancer and their partners experience.

Quick facts

• Study type: Observational
• Enrollment: 432 (estimated)
• Ages: 18 Years and up
• Sex: All
• Sponsor: University Hospital, Lille (other)
• Drugs / interventions: radiation
• Locations: 1 site (Lille)
• Trial ID: NCT07351461 on ClinicalTrials.gov

What this trial studies

This single-center observational study at Lille University Hospital will recruit men who began active surveillance for localized prostate cancer between 2007 and 2023 and their life partners. Participants will complete validated anxiety questionnaires and may be invited to qualitative interviews to describe emotional symptoms and coping. Clinical data from routine PSA tests, MRI scans, and biopsies will be combined with survey and interview data to explore factors linked to anxiety in both patients and partners. The aim is to better characterize the emotional burden and identify needs for targeted psychosocial support.

Who should consider this trial

Good fit: Ideal candidates are French-speaking adults (age ≥18) with localized prostate cancer who began active surveillance between 2007 and 2023, are followed at Lille University Hospital, have social security coverage, and have a life partner willing to participate.

Not a fit: Patients without a partner, those not followed at Lille University Hospital, non–French speakers, those lacking social security coverage, or men on definitive treatment rather than active surveillance are unlikely to benefit directly.

Why it matters

Potential benefit: If successful, the findings could lead to better-targeted psychological support and counseling to reduce anxiety and improve quality of life for patients and their partners.

How similar studies have performed: Previous research on anxiety during active surveillance has been limited and has mostly focused on patients alone, so jointly measuring patient and partner anxiety is relatively novel.

Eligibility criteria

Inclusion Criteria:

* Age ≥ 18 years.
* Patients who started active surveillance for localized prostate cancer from 2007 to 2023 and are followed in the Urology Department of Lille University Hospital.
* Affiliation to a social security scheme.
* Obtaining patient consent.
* Having a life partner or an unidentified partner recognized as the person sharing the patient's daily life

Exclusion Criteria:

* Lack of proficiency in the French language.
* Minor patients, those under legal protection measures, or deprived of liberty.
* Lack of medical insurance coverage.
* Patients refusing to participate in the study.

Where this trial is running

Lille

• CHU de Lille — Lille, France (RECRUITING)

Study contacts

• Study coordinator: Jonathan OLIVIER, Dr

Conditions: Prostate Cancer, Prostate cancer, Anxiety