Clinical trial Recruiting at 1 site Phase 1 Interventional Ages 16 to 50

Antivet and acids microabrasion for teeth stain in adults

Official title: Clinical Efficacy of Antivet Versus Phosphoric Acid and Hydrochloric Acid in Microabrasion Technique for Treatment of Stained Teeth: Randomized Clinical Trial

Run by Misr University for Science and Technology · NCT07709286 · Data updated 2026-11-12

This trial tests whether using Antivet cleaning solution plus acids in a microabrasion technique can improve mild to moderate tooth staining in people aged 16–50.

Quick facts

PhasePhase 1
Study typeInterventional
Ages16 Years to 50 Years
SexAll
Enrollment60 (estimated)
SponsorMisr University for Science and Technology
Academic / other
Locations1 site (Badr, Cairo Governorate)
StatusRecruiting
StartedJanuary 10, 2026
Main results expectedJuly 10, 2026
Study endsOctober 1, 2026
Registry record updatedJuly 16, 2026
Trial IDNCT07709286 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 16–50 with mild to moderate intrinsic or extrinsic anterior tooth stains who are cooperative.

Probably not a fit

Patients with high caries risk, poor oral hygiene, dental infections, or non-cooperative behavior may not benefit from this treatment.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional Phase 1 trial examines the clinical efficacy of combining Antivet with phosphoric acid and hydrochloric acid in a microabrasion procedure for intrinsic and extrinsic tooth stains. Participants will undergo standardized tooth preparation, isolation, and sequential application of Antivet and acid-based abrasives, with color photos taken before and after treatment. The procedure aims to determine how effectively the treatment removes stains while maintaining tooth surface integrity. Outcomes will focus on stain reduction and any procedure-related adverse effects.

Why it matters

Potential benefit: If successful, patients may experience improved tooth color and reduced staining with a minimally invasive procedure.

How similar studies have gone: Previous microabrasion approaches with enamel abrasives have shown stain reduction, though this exact combination with Antivet is novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
1. Eligibility Criteria of participants:

   Inclusion Criteria:
   * Patients with moderate to mild stained teeth.
   * 16-50 years.
   * Males or Females.
   * Co-operative patients approving to participate in the study.

   Exclusion Criteria:
   * High caries index with poor oral hygiene.
   * Severe medical complications.
   * Pregnancy.
   * Xerostomia.
   * Lack of compliance.
   * Smokers
2. Eligibility Criteria of teeth:

Inclusion Criteria of teeth:

* Anterior teeth.
* Mild to moderate intrinsic or extrinsic stains.
* Vital and non-sensitive anterior teeth.

Exclusion criteria of the teeth:

* pitted enamel.
* carious teeth.
* Deep lesions.
* Severe periodontal problems.
* Previous treatment for the stained teeth

Where it's running

  • Egyptian Russian University
    Badr, Cairo Governorate, Egypt
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.