Antioxidant-rich diet to lower metabolic syndrome risk
Assessing the Effect of an Antioxidant-Rich Diet on Metabolic Syndrome Risk Using the Dietary Antioxidant Index
This program will try an antioxidant-rich diet to see if it improves metabolic syndrome risk factors in urban adults aged 18–45 who eat fewer than five servings of fruits and vegetables per day.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 55 (estimated) |
| Ages | 18 Years to 45 Years |
| Sex | All |
| Sponsor | University of Veterinary and Animal Sciences, Lahore - Pakistan Academic / other |
| Locations | 1 site (Lahore, Punjab Province) |
| Trial ID | NCT07354438 on ClinicalTrials.gov |
What this trial studies
Researchers will enroll urban adults aged 18–45 at risk for metabolic syndrome (by NCEP ATP III and WHO criteria) in Lahore and collect dietary recalls and clinical measures before and after the intervention. Dietary data will be analyzed in NutriSurvey using the Pakistan Food Composition Table, with missing values supplemented from the Indian Food Composition Table, to calculate each participant's Dietary Antioxidant Index (DAI). Individuals identified with low DAI will receive an antioxidant-focused dietary intervention and have follow-up measurements of DAI and metabolic markers. Pre-post changes will be tested with paired t-tests and associations between DAI and metabolic risk factors will be examined using Pearson correlation in SPSS 25.
Who should consider this trial
Good fit: Ideal candidates are adults 18–45 with abdominal obesity and elevated blood pressure consistent with metabolic syndrome risk, who consume fewer than five servings of fruits and vegetables per day, are not pregnant or lactating, and are willing to follow the diet.
Not a fit: People outside the 18–45 age range, those already eating adequate fruits and vegetables, pregnant or lactating women, or individuals with chronic illnesses or malabsorption syndromes are unlikely to receive benefit from this intervention.
Why it matters
Potential benefit: If successful, the intervention could offer a low-cost dietary approach to reduce metabolic syndrome risk factors in urban Pakistani adults.
How similar studies have performed: International observational studies have linked higher Dietary Antioxidant Index scores with lower metabolic syndrome risk, but interventional evidence—especially in Pakistan—is limited.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults aged 18-45 years * Metabolic syndrome risk (abdominal obesity \& elevated BP as per NCEP ATP III criteria). * Low fruit \& veg intake (\<5 serv./day) as per WHO. * Willing to follow an intervention * Non-pregnant or lactating * Not diagnosed with malabsorption syndrome or chronic illness Exclusion Criteria: * Individuals \< 18 years or \> 45 years * Not at risk of metabolic syndrome. * Adequate intake of fruits \& veg (≥ 5 serv./day) as per WHO * Not willing * Pregnant or lactating * Diagnosed with malabsorption syndrome or chronic illness
Where this trial is running
Lahore, Punjab Province
- University of Veterinary & Animal Sciences, Lahore Pakistan — Lahore, Punjab Province, Pakistan (Recruiting)
Study contacts
- Principal investigator: Qaisar Raza, Ph.D — University of Veterinary & Animal Sciences, Lahore Pakistan.
- Study coordinator: Anaum Javed, PG
- Email: anaumjaved768@gmail.com
- Phone: +92-3040370308
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.