Anti-inflammatory lifestyle intervention for young cancer survivors
Feasibility and Acceptability of an Anti-Inflammatory Lifestyle Intervention for Emerging Adult Cancer Survivors
This study is testing a new lifestyle program aimed at helping young cancer survivors aged 18-29 reduce inflammation and see how well they can stick with it.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 19 (estimated) |
| Ages | 18 Years to 29 Years |
| Sex | All |
| Sponsor | Virginia Commonwealth University Academic / other |
| Drugs / interventions | chemotherapy, radiation |
| Locations | 1 site (Richmond, Virginia) |
| Trial ID | NCT06442397 on ClinicalTrials.gov |
What this trial studies
This pilot trial aims to evaluate the feasibility and acceptability of an anti-inflammatory lifestyle intervention (AILI) specifically designed for emerging adult cancer survivors aged 18-29. The study will involve 16 participants who will engage in lifestyle modifications aimed at reducing inflammation. The primary focus is to assess how well these individuals can adhere to the intervention and the overall acceptability of the program. The trial is single-arm, meaning all participants will receive the same intervention without a control group.
Who should consider this trial
Good fit: Ideal candidates for this study are emerging adult cancer survivors aged 18-29 with a body fat percentage above specified thresholds.
Not a fit: Patients currently undergoing active chemotherapy or radiation, or those with certain uncontrolled medical conditions, may not benefit from this study.
Why it matters
Potential benefit: If successful, this intervention could improve the health and quality of life for young cancer survivors by promoting healthier lifestyle choices.
How similar studies have performed: While this approach is relatively novel, similar lifestyle interventions have shown promise in other populations, suggesting potential for success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age 18-29 * Cancer diagnosis of any type * Body fat percentage \>16.2% for women; \>10.6% for men Exclusion Criteria: * Individuals receiving active chemotherapy/radiation or those having completed active chemotherapy/radiation within the past 6 months * Individuals who are currently pregnant or lactating * Current involvement in a weight loss program or current use of weight loss medication * Individuals who report any other uncontrolled medical conditions that may pose a safety issue given the recommendations for the diet and unsupervised physical activity (e.g., uncontrolled hypertension) * Individuals with rheumatologic and gastrointestinal conditions associated with severe systemic inflammation (e.g., rheumatoid arthritis, systemic lupus erythematosus, Crohn's disease) * Individuals with medical conditions resulting in known perturbations in the hypothalamic-pituitary-adrenal axis (e.g., endogenous hypercortisolemia \[Cushing's syndrome\] or adrenal insufficiency) * Individuals who report a heart condition, chest pain during periods of activity or rest, or loss of consciousness as assessed by the Physical Activity Readiness Questionnaire (PAR-Q) * Report of lifetime diagnosis of Anorexia Nervosa or Bulimia Nervosa, or any compensatory behaviors (vomiting, laxative abuse) within the previous 3 months * Hospitalization for depression or other psychiatric disorder within the past 12 months * Report of lifetime diagnosis of bipolar disorder or psychotic disorder * Indication of current suicidal intent * Inability to speak and read English
Where this trial is running
Richmond, Virginia
- Virginia Commonwealth University, School of Medicine — Richmond, Virginia, United States (Recruiting)
Study contacts
- Principal investigator: Autumn Lanoye, Ph.D — Virginia Commonwealth University
- Study coordinator: Tyler Phillips
- Email: phillipst5@vcu.edu
- Phone: 804-828-1965
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.