Anesthesia methods and recovery after HoLEP surgery
The Effect of Anesthesia Techniques on Quality of Recovery (QoR-40) Scores in Benign Prostatic Hyperplasia (Holmium Laser Enucleation of the Prostate - HoLEP) Surgery: A Cross-Sectional, Observational, Prospective Study
This project will see if general, spinal, or combined spinal-epidural anesthesia leads to better early recovery and satisfaction for men having HoLEP, using the QoR-40 score before and within 24 hours after surgery.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 450 (estimated) |
| Ages | 18 Years and up |
| Sex | Male |
| Sponsor | TC Erciyes University Academic / other |
| Locations | 1 site (Melikgazi, Kayseri) |
| Trial ID | NCT07020390 on ClinicalTrials.gov |
What this trial studies
This observational study compares three anesthesia approaches—general, spinal, and combined spinal-epidural—in men undergoing Holmium Laser Enucleation of the Prostate (HoLEP). Anesthesia choice follows routine clinical practice based on age, comorbidities, surgery duration, and patient preference, and is administered by an experienced anesthesiologist. Participants complete the QoR-40 questionnaire preoperatively and within 24 hours postoperatively, and investigators also record pain scores, analgesic use, catheter-related discomfort, and 5-point Likert satisfaction ratings from patients and surgeons. Results will be analyzed by anesthesia group to identify differences in early recovery and satisfaction.
Who should consider this trial
Good fit: Male patients with benign prostatic hyperplasia scheduled for HoLEP who can give informed consent, are cognitively intact, and are not taking psychoactive medications.
Not a fit: Patients with cognitive impairment, those using psychoactive drugs, patients who require intraoperative conversion of anesthesia, those needing reoperation or ICU care, or those who withdraw consent are unlikely to benefit from this study's results.
Why it matters
Potential benefit: If successful, the findings could help clinicians choose the anesthesia method that gives men faster, more comfortable recoveries and higher satisfaction after HoLEP.
How similar studies have performed: Previous work in urologic procedures has shown differences in pain and early recovery between spinal and general anesthesia, but direct comparative data specifically for HoLEP remain limited.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients scheduled for HOLEP surgery due to benign prostatic hyperplasia. * Patients who consent to participate in the study. Exclusion Criteria: * Refusal to participate in the study * Presence of cognitive impairment * Use of psychoactive medications * Failure of the intraoperative anesthesia technique and necessity to change the anesthesia method * Requirement for reoperation or admission to the intensive care unit * Voluntary withdrawal from the study
Where this trial is running
Melikgazi, Kayseri
- Erciyes University — Melikgazi, Kayseri, Turkey (Türkiye) (Recruiting)
Study contacts
- Study coordinator: Gamze Talih
- Email: gamzetalih@gmail.com
- Phone: +905447604780
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.