Clinical trial Recruiting at 1 site Observational Ages 18 and up

Analyzing the impact of hospital volume on esophageal cancer outcomes

Official title: Volume Outcome Relationships and Effects of Adjuvant and Neoadjuvant Therapy in Mortality in Esophageal Cancer

Run by Methodist Health System · NCT06343597 · Data updated 2026-11-12

This study looks at whether patients with esophageal cancer do better when treated at hospitals that perform more surgeries for this condition compared to those that do fewer.

More Esophageal Cancer trials

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment30 (estimated)
SponsorMethodist Health System
Academic / other
Locations1 site (Richardson, Texas)
StatusRecruiting
StartedJune 15, 2020
Main results expectedJune 15, 2027
Study endsJune 15, 2028
Registry record updatedMarch 20, 2026
Trial IDNCT06343597 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are patients diagnosed with esophageal cancer.

Probably not a fit

Patients without a diagnosis of esophageal cancer will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study conducts a retrospective analysis to evaluate whether patients with esophageal cancer experience different outcomes based on the volume of surgeries performed at their treating hospital. It compares high-volume facilities, which perform more than five esophagectomies per year, to low-volume facilities, which perform fewer than five. The study aims to clarify the relationship between hospital surgical volume and patient outcomes, including the effectiveness of neoadjuvant and adjuvant therapies. By understanding these dynamics, the research seeks to inform treatment assessments for esophageal cancer patients.

Why it matters

Potential benefit: If successful, this study could help identify optimal treatment settings for esophageal cancer, potentially improving patient outcomes.

How similar studies have gone: Previous studies have shown success in understanding volume-outcome relationships in other cancers, such as pancreatic cancer, suggesting potential relevance for esophageal cancer.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* esophageal cancer

Exclusion Criteria:

* No esophageal cancer

Where it's running

  • Methodist Richardson Medical Center
    Richardson, Texas, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.