Analyzing the impact of hospital volume on esophageal cancer outcomes

Volume Outcome Relationships and Effects of Adjuvant and Neoadjuvant Therapy in Mortality in Esophageal Cancer

Observational Methodist Health System · NCT06343597

This study looks at whether patients with esophageal cancer do better when treated at hospitals that perform more surgeries for this condition compared to those that do fewer.

Quick facts

Study typeObservational
Enrollment30 (estimated)
Ages18 Years and up
SexAll
SponsorMethodist Health System Academic / other
Locations1 site (Richardson, Texas)
Trial IDNCT06343597 on ClinicalTrials.gov

What this trial studies

This observational study conducts a retrospective analysis to evaluate whether patients with esophageal cancer experience different outcomes based on the volume of surgeries performed at their treating hospital. It compares high-volume facilities, which perform more than five esophagectomies per year, to low-volume facilities, which perform fewer than five. The study aims to clarify the relationship between hospital surgical volume and patient outcomes, including the effectiveness of neoadjuvant and adjuvant therapies. By understanding these dynamics, the research seeks to inform treatment assessments for esophageal cancer patients.

Who should consider this trial

Good fit: Ideal candidates for this study are patients diagnosed with esophageal cancer.

Not a fit: Patients without a diagnosis of esophageal cancer will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could help identify optimal treatment settings for esophageal cancer, potentially improving patient outcomes.

How similar studies have performed: Previous studies have shown success in understanding volume-outcome relationships in other cancers, such as pancreatic cancer, suggesting potential relevance for esophageal cancer.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* esophageal cancer

Exclusion Criteria:

* No esophageal cancer

Where this trial is running

Richardson, Texas

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Esophageal Cancer
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.