Analyzing sleep changes after anesthesia in patients with obstructive sleep apnea
The SNORE-trial: Postoperative REM-Sleep Disturbance iN Obstructive Sleep-apnea Patients and the Relation With AH-index
This study is testing how sleep patterns change after surgery in people with obstructive sleep apnea to see if these changes get worse over a few nights.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 35 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) Academic / other |
| Locations | 2 sites (Amsterdam, North Holland and 1 other locations) |
| Trial ID | NCT06586268 on ClinicalTrials.gov |
What this trial studies
This observational study aims to investigate how sleep patterns change following anesthesia and whether these changes correlate with the severity of obstructive sleep apnea (OSA) in patients after surgery. Participants diagnosed with OSA will wear a device called WATCHPAT to monitor their sleep stages and record incidents of apnea and hypopnea over three nights post-operatively. The study will assess whether the severity of OSA increases from the first to the third night after surgery and how this relates to REM sleep. Data will be collected non-invasively, allowing for a comprehensive analysis of sleep disturbances in the post-surgical period.
Who should consider this trial
Good fit: Ideal candidates are adults scheduled for elective surgery who have a diagnosis of obstructive sleep apnea, with or without treatment.
Not a fit: Patients under 18 years old or those not speaking Dutch or English may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved management strategies for patients with obstructive sleep apnea following surgery.
How similar studies have performed: While there have been studies on sleep apnea, this specific approach of analyzing post-anesthesia sleep changes is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients scheduled for elective surgery at the operating theatres of the AUMC with a diagnosis of OSA with or without treatment with an expected admittance of a minimum of 3 days * Patients with continuous positive airway pressure (CPAP) or mandibular advancement device (MAD) are considered patients with treatment for OSA * Patients ≥ 18 years * Dutch or English speaking * Willing and able to sign consent for re-use of care data Exclusion Criteria: * Patients \< 18 years * Not speaking Dutch or English * Patients who do not sign consent for re-use of care data * Surgery scheduled in day case or with an expected discharge before the third night after surgery
Where this trial is running
Amsterdam, North Holland and 1 other locations
- AmsterdamUMC, location AMC — Amsterdam, North Holland, Netherlands (Recruiting)
- Amsterdam UMC location VuMC — Amsterdam, Netherlands (Recruiting)
Study contacts
- Principal investigator: Jeroen Hermanides, Prof. Dr. — AmsterdamUMC
- Study coordinator: Martin V.H. Rutten, Msc, MD
- Email: m.v.rutten@amsterdamumc.nl
- Phone: +31205669111
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.