Analyzing risk factors for high eye pressure and retinal detachment recurrence after surgery
Analysis of Risk Factors for High Intraocular Pressure and Retinal Detachment Recurrence After Vitrectomy with Silicone Oil Tamponade in Retinal Detachment Patients
This study looks at patients who had surgery for retinal detachment to see what factors might lead to high eye pressure or the detachment coming back.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 65 (estimated) |
| Ages | 18 Years to 90 Years |
| Sex | All |
| Sponsor | First Affiliated Hospital of Chongqing Medical University Academic / other |
| Locations | 1 site (Chongqing, Chongqing Municipality) |
| Trial ID | NCT06826573 on ClinicalTrials.gov |
What this trial studies
This observational study will retrospectively analyze patients diagnosed with rhegmatogenous retinal detachment who underwent vitrectomy with silicone oil tamponade at the First Affiliated Hospital of Chongqing Medical University. Clinical data will be collected from patients who meet specific inclusion criteria, and various postoperative indicators will be recorded at multiple time points. The study aims to identify risk factors associated with high intraocular pressure and the recurrence of retinal detachment. Data will be statistically analyzed to draw meaningful conclusions about these risk factors.
Who should consider this trial
Good fit: Ideal candidates are adults over 18 years old diagnosed with rhegmatogenous retinal detachment and with normal intraocular pressure prior to surgery.
Not a fit: Patients with pre-existing high intraocular pressure or other significant ocular conditions such as glaucoma will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could help identify patients at higher risk for complications, leading to improved management and outcomes after retinal detachment surgery.
How similar studies have performed: While similar studies have explored risk factors in retinal detachment surgeries, this specific analysis of intraocular pressure and recurrence is novel and may provide new insights.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * 1\. Diagnosed with "rhegmatogenous retinal detachment". 2. Aged over 18 years old, with normal mental and psychological status, regardless of gender. 3\. Intraocular pressure of both eyes is less than 21 mmHg before surgery, and having no personal or family history of glaucoma. 4\. Cup - to - disc ratio (C/D) in fundus examination is less than 0.5 for both eyes. 5\. Those who understand the purpose of this study, sign the "Informed Consent Form" and have a high degree of compliance. Exclusion Criteria: \- 1. Those with high intraocular pressure before surgery and suffering from ophthalmic diseases such as glaucoma; 3. Those with acute or chronic systemic infections and hematological diseases; 4. Those with a history of mental and psychological diseases; 5. Those with incomplete survey data or unable to cooperate with this research. 5. Those with traumatic rhegmatogenous retinal detachment; 6. Those with active ocular infectious lesions in either eye; 7. Those with severe refractive media opacity (such as corneal nebula, corneal leukoma) in the target eye, which affects imaging examinations during postoperative follow - up. 8\. Those with a history of congenital structural abnormalities in the target eye; 9. Those who have undergone vitrectomy for other vitreoretinal diseases in the target eye before screening; 10. Those whom the researchers consider unfit to participate in this clinical trial.
Where this trial is running
Chongqing, Chongqing Municipality
- The First Affiliated Hospital of Chongqing Medical University — Chongqing, Chongqing Municipality, China (Recruiting)
Study contacts
- Study coordinator: Hui Peng
- Email: pengh9@sina.com
- Phone: 13072369950
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.