Analyzing retinal arteries in stroke patients using advanced imaging
Official title: Adaptive Optics (AO) Analysis of Retinal Arteries in Patients With Recent Stroke (STROKAO)
Run by Fondation Ophtalmologique Adolphe de Rothschild · NCT04712747 · Data updated 2026-05-14
This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.
This study is testing a new imaging technique to look at the blood vessels in the eyes of stroke patients to see how they might be affected by the stroke.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 100 (estimated) |
| Sponsor | Fondation Ophtalmologique Adolphe de Rothschild Research network |
| Locations | 1 site (Paris) |
| Trial ID | NCT04712747 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include inpatients with confirmed stroke occurring within the last 10 days.
✕Probably not a fit
Patients with hemorrhagic post-traumatic hematoma strokes or those with insufficient consciousness to undergo the examination may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study utilizes adaptive optics to analyze the retinal vascular system in patients who have experienced a recent stroke. By employing advanced imaging techniques, the study aims to visualize and measure various structural parameters of retinal vessels, which may provide insights into the microvascular changes associated with stroke. The research includes both stroke patients and matched controls to enhance the understanding of retinal changes in relation to stroke pathology. The findings could lead to improved monitoring and treatment strategies for stroke patients.
Why it matters
Potential benefit: If successful, this study could enhance the understanding of stroke-related microvascular changes and improve patient management.
How similar studies have gone: Other studies utilizing adaptive optics for retinal imaging have shown promise, indicating potential for success in this novel application.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * For the patients with stroke: Inpatients with confirmed stroke (clinical and imaging) for less than 10 days * For the controls: Individuals presenting at the Rothschild Foundation Hospital with no history of stroke who are matched to cases already included in the matching criteria: Age ± 5 years, Gender, high blood pressure (no history, untreated, treated) Diabetes (Yes, No), Body Mass Index (BMI \< 25, 25 ≥ BMI \< 30, BMI ≥ 30) Exclusion Criteria: * Pregnant or breastfeeding woman * Insufficient state of consciousness or physical condition to perform the adaptive optics examination * For the patients with stroke: Hemorrhagic post-traumatic hematoma stroke type, or symptomatic stroke of a brain tumour or an arteriovenous malformation.
Where it's running
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Hôpital Fondation A. de Rothschuld
Paris, France Recruiting
Study contacts
- Principal investigator: Martine MAUGET FAYSSE, MD — Hôpital Fondation A. de Rothschild
- Study coordinator: Amélie YAVCHITZ, MD
- Email: ayavchitz@for.paris
- Phone: 01 48 03 64 54
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Deep phenotyping to explore recovery in young adults after stroke
This project will test whether a detailed health and sample-collection approach (deep phenotyping) is practical and acceptable for people aged 18–55 who have had a stroke.
-
Stem cell therapy for chronic stroke recovery
This study is testing whether using a patient's own stem cells can help people with long-term stroke recovery feel better and improve their daily functioning.
-
AI-based tools to help diagnose, treat and predict stroke outcomes across multiple hospitals
This study tests AI-powered tools on real-world stroke patients to see if they can improve pre-hospital triage, diagnosis, and outcome prediction while data stay securely within each hospital.
-
Web-based therapy using action observation and mirror therapy for arm weakness after stroke
This trial tests whether a mobile telerehabilitation app delivering action observation therapy (AOT) alone or combined AOT with mirror therapy (AOT-MT) can improve upper limb function in people with subacute stroke.
-
Remote Ischaemic Conditioning for Fatigue After Stroke 2
Aat least 12 weeks after stroke, adults with post-stroke fatigue will try a simple hand-arm cuff treatment at home to see if it helps reduce fatigue.
-
Dual-task balance training plus computer-based cognitive training after stroke
In adults who recently had a stroke, the study tests whether adding computerized cognitive exercises to balance training improves balance and other recovery outcomes.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.