Analyzing protein levels in the blood of people with knee osteoarthritis
Analysis of Protein Expression in Serum of Subjects With Knee Arthritis Control Group and Evaluation by Meridian and Pulse Wave Energy
NA · China Medical University Hospital · NCT06553313
This study is testing the protein levels in the blood of people with knee osteoarthritis compared to those without knee pain to help understand the condition better.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 50 (estimated) |
| Ages | 50 Years and up |
| Sex | All |
| Sponsor | China Medical University Hospital (other) |
| Locations | 1 site (Taichung) |
| Trial ID | NCT06553313 on ClinicalTrials.gov |
What this trial studies
This study aims to analyze protein expression in the serum of individuals with knee osteoarthritis (KOA) by comparing it to a control group. Building on previous findings that acupuncture significantly affects serum protein profiles in KOA patients, this research will gather data from adults over 50 years old who do not have knee pain. The study will utilize a Micro-Western Array to measure protein levels and will also assess pulse wave energy values. The results will help establish standard values for serum protein expression in KOA, facilitating future comparisons.
Who should consider this trial
Good fit: Ideal candidates for this study are adults over 50 years old who do not experience knee pain.
Not a fit: Patients with a clinical diagnosis of knee osteoarthritis or those who have recently taken anti-inflammatory medications or received acupuncture treatment may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide valuable insights into the biological markers of knee osteoarthritis, aiding in better diagnosis and treatment strategies.
How similar studies have performed: While this approach builds on previous findings related to acupuncture and KOA, the specific analysis of serum protein expression in a control group is a novel aspect.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults over 50 years old without knee pain Exclusion Criteria: 1. Clinical diagnosis of knee osteoarthritis 2. Taking anti-inflammatory and analgesic drugs in the past month 3. Taking blood-lipid-lowering drugs or health foods in the past month 4. Received any acupuncture treatment in the past 3 weeks
Where this trial is running
Taichung
- China Medical University — Taichung, Taiwan (RECRUITING)
Study contacts
- Principal investigator: Wan-Zhen Yu — China Medical University, China
- Study coordinator: Wan-Zhen Yu
- Email: a030037@gmail.com
- Phone: 8864-22053366
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Knee Osteoarthritis