Analyzing plant-related allergies using skin tests
Official title: Analysis of the Prevalence of Sensitization to Plants Containing Gibberellins Using Realistic Skin Prick Tests in a Population of Patients Attending the Montpellier University Hospital.
Run by University Hospital, Montpellier · NCT06183398 · Data updated 2026-11-12
This study is testing if people with allergies, especially those living in areas with a lot of pollen, are sensitive to certain proteins in peach pollen and other foods by using skin tests.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 5 Years and up |
| Sex | All |
| Enrollment | 2000 (estimated) |
| Sponsor | University Hospital, Montpellier Academic / other |
| Locations | 1 site (Montpellier) |
| Status | Recruiting |
| Started | March 14, 2024 |
| Main results expected | March 14, 2028 |
| Study ends | March 14, 2028 |
| Registry record updated | October 3, 2025 |
| Trial ID | NCT06183398 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include patients aged 5 years and older who are seeking evaluation for allergies at the University Hospital of Montpellier.
✕Probably not a fit
Patients with conditions that prevent skin prick testing or those currently taking antihistamines may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates the prevalence of sensitization to gibberellin-related proteins (GRPs) found in pollens and certain foods, particularly focusing on the allergen Pru p 7 from peaches. It aims to determine the extent of sensitization in patients consulting the Allergy Unit at the University Hospital of Montpellier, especially in regions with high pollen exposure. Participants will undergo skin prick tests to assess their allergic responses to GRPs and potential cross-reactivity with other foods. The findings could provide valuable insights into the relationship between environmental allergens and food allergies.
Why it matters
Potential benefit: If successful, this study could enhance the understanding of food allergies related to plant proteins, leading to better diagnosis and management for affected patients.
How similar studies have gone: While there has been limited analysis on the prevalence of sensitization to GRPs, this approach is novel and has not been extensively tested in prior studies.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients aged at least 5 years * Patients consulting at the Allergy Unit of the University Hospital of Montpellier for any type of allergy work-up/evaluation * Oral consent from the patient and, where applicable, from at least one of the patient's legal representatives in the case of minors. Exclusion Criteria: * Patients treated with antihistamines or psychotropic drugs with antihistaminic action during the 7 days prior to inclusion * Patients with pathologies that prevent the performance of prick tests (e.g. severe peripheral neuropathy, cutaneous anergy). * Patients with dermographism. * Patient taking part in another study which may influence the results of the prick tests. * Patients in an exclusion period determined by a previous study. * Pregnant, parturient or breast-feeding women. * Patients or their legal representatives under court protection, guardianship or trusteeship. * Patients or their legal representatives who are not members or beneficiaries of a health insurance scheme. * Patient or his/her legal representative unable to read and understand French fluently.
Where it's running
-
University Hospital of Montpellier
Montpellier, France Recruiting
Study contacts
- Principal investigator: Davide CAIMMI, MD — University Hospital, Montpellier
- Study coordinator: Davide CAIMMI, MD
- Email: dp-caimmi@chu-montpellier.fr
- Phone: +33467336112
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.