Analyzing non-invasive methods for liver lesions in cirrhosis patients
Official title: Non-Invasive Characterization of Focal Liver Lesions in Liver Cirrhosis
Run by University Hospital, Bonn · NCT03746210 · Data updated 2026-11-12
This study is testing new non-invasive imaging methods to see if they can accurately identify liver lesions in patients with cirrhosis and predict their treatment outcomes and survival.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 99 Years |
| Sex | All |
| Enrollment | 200 (estimated) |
| Sponsor | University Hospital, Bonn Academic / other |
| Locations | 1 site (Bonn) |
| Status | Recruiting |
| Started | January 1, 2016 |
| Main results expected | December 31, 2025 |
| Study ends | December 31, 2027 |
| Registry record updated | May 18, 2022 |
| Trial ID | NCT03746210 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include adults with liver cirrhosis who have focal liver lesions.
✕Probably not a fit
Patients who do not consent to participate or are under 18 years old will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study focuses on the non-invasive characterization of focal liver lesions in patients diagnosed with liver cirrhosis. It employs multiparametric ultrasound imaging and evaluates sarcopenia parameters to assess the diagnostic accuracy and predictive value of these non-invasive methods. The primary endpoint involves comparing the results to established gold standards such as CT, MRI, or histology, while the secondary endpoint examines the predictive value concerning mortality and treatment response. All procedures follow standard care protocols.
Why it matters
Potential benefit: If successful, this study could enhance the diagnostic accuracy for liver lesions, leading to better patient management and outcomes.
How similar studies have gone: Other studies have shown promise in using non-invasive methods for liver diagnostics, suggesting potential success for this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * all patients with focal liver lesions and liver cirrhosis Exclusion Criteria: * no consent * under 18 years
Where it's running
-
University Hospital Bonn
Bonn, Germany Recruiting
Study contacts
- Study coordinator: Michael Praktiknjo, MD
- Email: michael.praktiknjo@ukbonn.de
- Phone: +4922828715770
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.