Analyzing MRI techniques for degenerative spine disease

MRI Analysis and Degenerative Spine

Universidade Nova de Lisboa · NCT06163300

This study looks at how advanced MRI scans can help doctors understand the condition of compressed nerve roots in people with degenerative spine disease and see how it changes with treatment.

Quick facts

Study typeObservational
Enrollment200 (estimated)
Ages50 Years to 85 Years
SexAll
SponsorUniversidade Nova de Lisboa (other)
Locations1 site (Setúbal)
Trial IDNCT06163300 on ClinicalTrials.gov

What this trial studies

This observational study focuses on the advanced analysis of MRI techniques to assess the microstructural integrity of compressed nerve roots in patients with degenerative spinal disease. It aims to identify image biomarkers affected by the disease and to understand how these biomarkers evolve with disease progression and treatment. The study will involve patients diagnosed with spinal disease, utilizing MRI to gather data on their condition over time.

Who should consider this trial

Good fit: Ideal candidates are individuals aged 50 to 85 years with a diagnosis of spinal disease lasting more than three months.

Not a fit: Patients who have undergone previous spine surgery or have significant neurological or orthopedic conditions may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved diagnostic techniques and treatment strategies for patients with degenerative spinal disease.

How similar studies have performed: While this approach is innovative, similar studies using advanced MRI techniques have shown promise in other areas of spinal research.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age between 50 and 85 years
* Diagnosis of spinal disease by clinical and imagiological criteria
* More than 3 months duration of disease
* Ability to give consent
* Fluent portuguese speaker

Exclusion Criteria:

* Previous spine surgery
* Spinal instability
* Neurological disease that might interfere with walking
* Known orthopedic conditions that causes significant gait impairment
* Dementia or development disorder with cognitive impairment
* Inability to give consent

Where this trial is running

Setúbal

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Spine Disease

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.