Analyzing liver lesions using advanced ultrasound imaging techniques

Research on Key Techniques for Intelligent Diagnosis and Ablation Decision-making of Liver Cancer and Evolution by Contrast-enhanced Ultrasound

Observational Chinese PLA General Hospital · NCT04682886

This study is testing a new ultrasound technique to see if it can help doctors better identify and understand liver lesions.

Quick facts

Study typeObservational
Enrollment5000 (estimated)
SexAll
SponsorChinese PLA General Hospital Academic / other
Drugs / interventionsradiation
Locations1 site (Beijing, Beijing)
Trial IDNCT04682886 on ClinicalTrials.gov

What this trial studies

This study focuses on enhancing the diagnosis of focal liver lesions (FLLs) through contrast-enhanced ultrasound (CEUS) imaging. It aims to collect standard data from CEUS recordings and develop a deep learning model to improve the segmentation, detection, and classification of liver lesions. By leveraging digital information technology, the study seeks to address challenges such as interobserver variability and the dependence on clinician experience. The ultimate goal is to create an intelligent diagnostic system that can provide more accurate assessments of liver lesions.

Who should consider this trial

Good fit: Ideal candidates include patients with solid liver tumors that are visible during routine ultrasound and have undergone CEUS.

Not a fit: Patients with hypersensitivity to ultrasound contrast media, pregnant or lactating individuals, or those with previously treated lesions will not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could lead to more accurate and reliable diagnoses of liver lesions, improving patient outcomes.

How similar studies have performed: While the use of CEUS for liver lesion diagnosis is established, the integration of deep learning for improved accuracy represents a novel approach that has not been extensively tested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. patients with a solid liver tumor visible during routine ultrasound and received CEUS.
2. disease history and standard of reference of the lesions can be acquired

Exclusion Criteria:

1. hypersensitivity for ultrasound contrast media
2. pregnant or lactating patients
3. previously treated lesions or local relapse from previously treated lesions
4. diffuse tumors

Where this trial is running

Beijing, Beijing

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Focal Liver LesionsContrast-enhanced Ultrasound
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.