Analyzing liver disease patients with hepatopulmonary syndrome

Analysis of Clinical Features of Chronic Liver Disease Complicated With Hepatopulmonary Syndrome

Observational Beijing YouAn Hospital · NCT05932927

This study looks at patients with chronic liver disease and hepatopulmonary syndrome to see how the condition affects them and to gather information that could help improve diagnosis and treatment.

Quick facts

Study typeObservational
Enrollment500 (estimated)
Ages18 Years to 100 Years
SexAll
SponsorBeijing YouAn Hospital Academic / other
Locations1 site (Beijing)
Trial IDNCT05932927 on ClinicalTrials.gov

What this trial studies

This observational study aims to investigate the clinical features of patients with hepatopulmonary syndrome (HPS) who also have chronic liver disease. The researchers will diagnose HPS based on established guidelines, collect clinical data, evaluate disease severity, and conduct follow-up management. Additionally, blood samples will be collected for proteomic analysis to better understand the underlying mechanisms of HPS and improve diagnostic and treatment strategies.

Who should consider this trial

Good fit: Ideal candidates for this study are patients with chronic liver disease who have agreed to participate in blood collection.

Not a fit: Patients with primary pulmonary diseases or acute gastrointestinal bleeding may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance the understanding and management of hepatopulmonary syndrome in patients with chronic liver disease.

How similar studies have performed: While the specific approach of this study is novel, similar studies have explored the clinical characteristics of HPS, indicating potential for valuable insights.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* chronic hepatitis Agreed to venous blood collection

Exclusion Criteria:

* pneumonia, pulmonary vascular disease, interstitial pulmonary disease, COPD, bronchial asthma, lung cancer and other primary pulmonary diseases, acute upper gastrointestinal bleeding.

Where this trial is running

Beijing

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Hepatopulmonary Syndrome
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.