Analyzing genetic and biological markers in idiopathic pulmonary fibrosis
Genomic and Proteomic Analysis of Disease Progression in Idiopathic Pulmonary Fibrosis
This study is trying to find out if certain genetic and biological markers can help predict how lung function will change over time in people with idiopathic pulmonary fibrosis.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 500 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of Pittsburgh Academic / other |
| Locations | 1 site (Pittsburgh, Pennsylvania) |
| Trial ID | NCT00373841 on ClinicalTrials.gov |
What this trial studies
This observational study aims to identify genetic and biological markers that may predict the decline in lung function in patients with idiopathic pulmonary fibrosis (IPF). Participants, who must be treated at the Simmons Center, will undergo various tests including blood draws, pulmonary function tests, echocardiograms, and CT scans, along with completing questionnaires about their symptoms. Follow-up visits will occur every 3-4 months to collect additional blood samples and assess changes in symptoms. If a patient experiences a rapid decline in lung function, a bronchoscopy will be performed to gather further data for analysis.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 or older diagnosed with idiopathic pulmonary fibrosis who are receiving treatment at the Simmons Center.
Not a fit: Patients with other lung illnesses will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved predictions of lung function decline in IPF patients, allowing for timely interventions.
How similar studies have performed: Other studies have shown promise in identifying biomarkers for disease progression in similar conditions, suggesting potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients who are 18 or older * Diagnosis of Idiopathic Pulmonary Fibrosis * Treated at the Simmons Center Exclusion Criteria: * Other Lung Illness
Where this trial is running
Pittsburgh, Pennsylvania
- Michelle F MacPherson — Pittsburgh, Pennsylvania, United States (Recruiting)
Study contacts
- Principal investigator: Kevin F Gibson, MD — University of Pittsburgh - Dorothy P. and Richard P. Simmons Center for Interstitial Lung Disease
- Study coordinator: Michelle MacPherson, MAT
- Email: macphersonmj@upmc.edu
- Phone: 412-647-4537
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.