Analyzing Damage Control Surgery for Severe Diverticulitis
An International Study Investigating the Adoption and Outcome of Damage Control Surgery in Hinchey III-IV Acute Diverticulitis (DACOSAD)
This study is testing if a special type of surgery for severe diverticulitis can help patients recover better and have fewer complications compared to regular surgery.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 300 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Link Campus University Academic / other |
| Locations | 9 sites (Santiago and 8 other locations) |
| Trial ID | NCT06428370 on ClinicalTrials.gov |
What this trial studies
This observational study aims to evaluate the effectiveness of damage control surgery, which includes bowel resection, open abdomen management, and delayed anastomosis, in treating patients with Hinchey III or IV diverticulitis. The study focuses on patients who have undergone surgery for severe cases of diverticulitis, particularly those experiencing septic shock or significant peritoneal contamination. By comparing outcomes with traditional surgical methods, the study seeks to determine if damage control surgery can reduce complications and improve recovery times.
Who should consider this trial
Good fit: Ideal candidates are adults over 18 years old who have undergone surgery for Hinchey III or IV diverticulitis.
Not a fit: Patients under 18 years old or those not undergoing surgery for the specified conditions may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to better surgical outcomes and reduced morbidity for patients with severe diverticulitis.
How similar studies have performed: Previous studies have indicated that damage control surgery may reduce the need for more invasive procedures like the Hartmann procedure, suggesting potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients \>18 year-old underwent surgery for Hinchey III and IV and submitted to resection, clip and drop, and open abdomen Exclusion Criteria: * Subjects \<18 year-old
Where this trial is running
Santiago and 8 other locations
- Hospital de Urgencia Asistencia Publica — Santiago, Chile (Enrolling_by_invitation)
- Fondazione Policlinico Universitario Campus Bio-Medico — Rome, Lazio, Italy (Recruiting)
- UOC Chirurgia Generale - Ospedale GB Grassi — Ostia Antica, Roma, Italy (Recruiting)
- UOC Chirurgia Generale Ospedale Coniugi Bernardini — Palestrina, Roma, Italy (Recruiting)
- UOC Chirurgia Generale Ospedale Sant'Anna e San Sebastiano — Caserta, Italy (Recruiting)
- UOC Chirurgia Generale, Urgenza e Trauma Pisa University Hospital — Pisa, Italy (Recruiting)
- Fondazione Policlinico Universitario "A.Gemelli" — Roma, Italy (Recruiting)
- UOC Chirurgia Generale ed Urgenza Ospedale Santo Spirito in Sassia — Roma, Italy (Recruiting)
- Dipartimento di Chirurgia AOU Policlinico Umberto I Sapienza Università di Roma — Roma, Italy (Recruiting)
Study contacts
- Study coordinator: Gianluca Costa, Prof.
- Email: g.costa@unilink.it
- Phone: +39 06 22541 8851
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.