Analyzing children with congenital diarrhea and enteropathy in China
Official title: A Case-control Study of Phenotype and Multi-omics Analysis of Children With Congenital Diarrhea and Enteropathy in China
Run by Children's Hospital of Fudan University · NCT06356545 · Data updated 2026-11-12
This study is trying to find out more about children in China with congenital diarrhea and enteropathy by looking for signs of the condition and creating a database to help manage it better.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 1 Month to 3 Years |
| Sex | All |
| Enrollment | 60 (estimated) |
| Sponsor | Children's Hospital of Fudan University Academic / other |
| Locations | 1 site (Shanghai, Shanghai Municipality) |
| Status | Recruiting |
| Started | April 15, 2024 |
| Main results expected | April 2026 |
| Study ends | October 2026 |
| Registry record updated | September 10, 2025 |
| Trial ID | NCT06356545 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include children with chronic diarrhea lasting more than two months or over one month for those under two months of age, whose parents or legal guardians provide consent.
✕Probably not a fit
Patients with chronic diarrhea caused by specific infections or conditions such as necrotizing enterocolitis or short bowel syndrome may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to establish a clinical cohort of children suffering from congenital diarrhea and enteropathy (CODE) in China. Researchers will utilize multi-omics technology to identify biomarkers associated with CODE and develop a clinical phenotype database. Additionally, the study will employ artificial intelligence to construct a clinical risk prediction model to better understand and manage this condition.
Why it matters
Potential benefit: If successful, this study could lead to improved diagnosis and management strategies for children with congenital diarrhea and enteropathy.
How similar studies have gone: While similar studies utilizing multi-omics approaches have shown promise in other conditions, this specific application in congenital diarrhea and enteropathy is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with chronic diarrhea lasting greater than 2 months or greater than 1 month in patients younger than 2 months of age * Patients with consent from parents or legal guardians Exclusion Criteria: * Chronic diarrhea caused by specific infections, i.e. CMV, Clostridioides difficile * Chronic diarrhea with necrotizing enterocolitis, short bowel syndrome * Functional diarrhea * Patients with poor compliance
Where it's running
-
Yanqiu Wang
Shanghai, Shanghai Municipality, China Recruiting
Study contacts
- Study coordinator: Ying Huang, MD,PHD
- Email: yhuang815@163.com
- Phone: +862164931727
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Comparing whole genome sequencing and whole exome sequencing for congenital diarrhea
This study is testing if whole genome sequencing can help doctors better diagnose and treat patients with congenital diarrhea compared to whole exome sequencing.
-
BioAmicus Complete probiotic drops for infant tummy and skin issues
This test will see if daily BioAmicus Complete probiotic drops help infants (about 1 to 4 months old) with colic, constipation, diarrhea, reflux, or atopic dermatitis.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.