Analyzing carotid graft interposition techniques after endarterectomy
The Role of Maintaining External Carotid Artery Flow in Graft Interposition After Carotid Endarterectomy
This study is testing whether keeping blood flow through the external carotid artery during surgery helps patients with narrowed carotid arteries have better outcomes after their procedures.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 250 (estimated) |
| Ages | 50 Years to 90 Years |
| Sex | All |
| Sponsor | Institute for Cardiovascular Diseases Dedinje Academic / other |
| Locations | 1 site (Belgrade) |
| Trial ID | NCT06528717 on ClinicalTrials.gov |
What this trial studies
This study examines the outcomes of carotid graft interposition procedures, focusing on the impact of maintaining blood flow through the external carotid artery during surgery. It involves patients with significant carotid artery stenosis who are at high risk for stroke. The research compares results from procedures that preserve external carotid artery flow against those that do not, aiming to determine the best surgical approach for these patients. The study is observational and will analyze data from patients undergoing these procedures at a specialized cardiovascular institute.
Who should consider this trial
Good fit: Ideal candidates include patients with symptomatic carotid stenosis greater than 50% or unilateral/bilateral asymptomatic stenosis greater than 60%.
Not a fit: Patients with carotid restenosis, recent major surgery, previous brain trauma or surgery, malignant disease, epilepsy, or carotid artery aneurysm may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve surgical outcomes and reduce stroke risk for patients undergoing carotid artery procedures.
How similar studies have performed: While there have been studies on carotid endarterectomy techniques, this specific approach of preserving external carotid artery flow is less commonly explored, making it a novel investigation.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * symptomatic carotid stenosis (\> 50%) * unilateral asymptomatic carotid stenosis (\> 60%) * bilateral asymptomatic carotid stenosis (\> 60%) Exclusion Criteria: * carotid restenosis * "major surgery" in previous 6 months * previous brain trauma or surgery * malignant disease * epilepsy * carotid artery aneurysm
Where this trial is running
Belgrade
- Institute for Cardiovascular Diseases Dedinje — Belgrade, Serbia (Recruiting)
Study contacts
- Study coordinator: Slobodan Pesic, MD
- Email: spesic90@gmail.com
- Phone: 00381616303360
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.