Analyzing cancer-related substances in lung cancer patients with brain metastasis
Official title: Comprehensive Profiling of Promising Biomarkers in Exosomes From Non-small Cell Lung Cancer With Central Nervous System Metastasis
Run by National Taiwan University Hospital · NCT06026735 · Data updated 2026-11-12
This study is testing whether certain substances found in the blood and spinal fluid of lung cancer patients with brain metastasis can help predict how the cancer will behave and how well treatments might work.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 20 Years to 90 Years |
| Sex | All |
| Enrollment | 30 (estimated) |
| Sponsor | National Taiwan University Hospital Academic / other |
| Locations | 1 site (Taipei) |
| Status | Recruiting |
| Started | January 13, 2023 |
| Main results expected | December 2027 |
| Study ends | December 2027 |
| Registry record updated | September 7, 2023 |
| Trial ID | NCT06026735 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include non-small cell lung cancer patients diagnosed with brain or meningeal metastases who are scheduled for surgical intervention.
✕Probably not a fit
Patients without brain or meningeal metastases or those whose physical condition prevents surgical intervention may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study focuses on non-small cell lung cancer patients who have developed central nervous system metastasis. It involves collecting cerebrospinal fluid, blood samples, and tumor tissue from patients undergoing surgical procedures. The study aims to analyze the exosomes present in these samples and correlate them with clinical data to determine if these cancer cell-related substances can serve as predictive indicators for lung cancer metastasis and treatment efficacy.
Why it matters
Potential benefit: If successful, this study could provide new bioindicators for predicting lung cancer metastasis and treatment response, potentially improving patient management.
How similar studies have gone: While similar studies have explored cancer biomarkers, this specific approach focusing on exosomes in cerebrospinal fluid and tumor tissue is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: \- A. Non-small cell lung cancer patients diagnosed with brain metastases or meningeal metastases on brain computed tomography (CT) or magnetic resonance (MRI) images. B. Patients with non-small cell lung cancer who are about to undergo surgical brain surgery, such as brain tumor resection, lumbar abdominal drainage, Euclidean storage, or ventriculoperitoneal drainage. Exclusion Criteria: \- A. Non-small cell lung cancer patients without brain metastases or meningeal metastases. B. Physical condition does not allow surgical removal of the tumor.
Where it's running
-
National Taiwan University Hospital
Taipei, Taiwan Recruiting
Study contacts
- Study coordinator: Abel Huang, Md
- Email: how.how0622@gmail.com
- Phone: +8860223123456
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.