Analyzing blood samples for pediatric solid tumors

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to determine the feasibility of detecting tumor-derived material in the blood of pediatric patients with solid tumors. By collecting serial blood samples from patients at various stages of treatment, including before, during, and after therapy, the study will analyze cell-free DNA, RNA, and other tumor-related substances. The findings will be correlated with traditional disease evaluation methods to assess the effectiveness of liquid biopsies in monitoring disease progression and treatment response.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Newly diagnosed, relapsed, or refractory histologically confirmed high grade bone or soft tissue sarcoma or malignant renal, thyroid, germ cell, or hepatic tumors, OR
* Healthy individual with no history of cancer or chronic medical problems and \< 21 years of age

Exclusion Criteria:

* CNS Malignancies
* Individuals \< 6 months of age

Where it's running

• Children's Hospital Los Angeles
  Los Angeles, California, United States Recruiting

Study contacts

• Principal investigator: Fariba Navid, MD — Children's Hospital Los Angeles
• Study coordinator: Fariba Navid, MD
• Email: fnavid@chla.usc.edu
• Phone: 323-361-2529

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.