Analyzing blood miRNAs to improve adenomyosis diagnosis
New Perspectives in Adenomyosis Pathogenesis With Epigenetic Analysis and miRNAs
This study is trying to see if certain tiny molecules in the blood can help doctors diagnose adenomyosis more easily by comparing samples from patients with the condition to those without it.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 50 (estimated) |
| Ages | 18 Years and up |
| Sex | Female |
| Sponsor | Université Catholique de Louvain Academic / other |
| Locations | 1 site (Brussels, Woluwe-Saint-Lambert) |
| Trial ID | NCT06373822 on ClinicalTrials.gov |
What this trial studies
This observational study aims to identify differentially expressed microRNAs (miRNAs) in the blood of patients with adenomyosis to develop new diagnostic methods. The researchers will collect blood samples from 25 adenomyosis patients and 25 healthy controls, isolating and analyzing miRNAs to detect potential differences. The hypothesis is that circulating miRNAs may serve as noninvasive biomarkers for diagnosing adenomyosis, based on previous findings in related conditions. The study will contribute to establishing a diagnostic panel that could be validated in larger populations in the future.
Who should consider this trial
Good fit: Ideal candidates for this study are pre-menopausal women aged 18 and older who have been diagnosed with adenomyosis.
Not a fit: Patients with HIV or Hepatitis, those who have participated in another clinical study in the past year, or those presenting symptoms of endometriosis may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to a noninvasive diagnostic tool for adenomyosis, improving early detection and treatment options for patients.
How similar studies have performed: Previous studies have shown success in using circulating miRNAs as diagnostic tools in related conditions, suggesting potential for this approach in adenomyosis.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥ 18 years * Pre-menopausal Exclusion Criteria: * HIV or Hepatitis-positive * having participated in another clinical study in the 12 months prior to recruitment * presenting symptoms of endometriosis
Where this trial is running
Brussels, Woluwe-Saint-Lambert
- Cusl — Brussels, Woluwe-Saint-Lambert, Belgium (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.