Analyzing biological samples from skull base tumors
Molecular and Cellular Characterization of Skull Base Tumors
University of Pittsburgh · NCT03759717
This study is testing how analyzing samples from skull base tumors can help identify new tumor types and improve treatment options for patients.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 4000 (estimated) |
| Sex | All |
| Sponsor | University of Pittsburgh (other) |
| Drugs / interventions | chemotherapy, radiation |
| Locations | 1 site (Pittsburgh, Pennsylvania) |
| Trial ID | NCT03759717 on ClinicalTrials.gov |
What this trial studies
This study focuses on the molecular and cellular characterization of skull base tumors by analyzing biological samples and genetic material. The aim is to identify new molecular features that can redefine tumor subtypes and improve patient management strategies. By comparing primary and recurrent tumors, the study seeks to uncover changes that occur after treatment, which may lead to novel chemotherapeutic options. The findings could enhance the understanding of tumor behavior and inform personalized treatment approaches.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals diagnosed with a skull base tumor.
Not a fit: Patients who do not have sufficient tumor samples at the time of resection will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to more accurate diagnoses and tailored treatment plans for patients with skull base tumors.
How similar studies have performed: While this approach is innovative, similar studies have shown promise in characterizing tumors at a molecular level, suggesting potential for success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Diagnosis of a skull base tumor Exclusion Criteria: * Insufficient tumor sample at time of resection
Where this trial is running
Pittsburgh, Pennsylvania
- University of Pittsburgh Medical Center — Pittsburgh, Pennsylvania, United States (RECRUITING)
Study contacts
- Principal investigator: Paul Gardner, MD — Associate Professor
- Study coordinator: Benita Valappil, MPH
- Email: valappilb2@upmc.edu
- Phone: 412-864-1744
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Skull Base Neoplasm, Cellular Pathology