Analyzing biological samples from skull base tumors

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study focuses on the molecular and cellular characterization of skull base tumors by analyzing biological samples and genetic material. The aim is to identify new molecular features that can redefine tumor subtypes and improve patient management strategies. By comparing primary and recurrent tumors, the study seeks to uncover changes that occur after treatment, which may lead to novel chemotherapeutic options. The findings could enhance the understanding of tumor behavior and inform personalized treatment approaches.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Diagnosis of a skull base tumor

Exclusion Criteria:

* Insufficient tumor sample at time of resection

Where it's running

• University of Pittsburgh Medical Center
  Pittsburgh, Pennsylvania, United States Recruiting

Study contacts

• Principal investigator: Paul Gardner, MD — Associate Professor
• Study coordinator: Benita Valappil, MPH
• Email: valappilb2@upmc.edu
• Phone: 412-864-1744

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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  This study is testing if regular MRI scans can help predict how radiation treatment affects healthy tissues in patients with tumors in the mouth or skull base.

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  Recruiting at 11 sites Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta · Bergamo, BG and 26 other locations · NCT06724029

• Evaluating a new hydrogel for healing after skull base surgery

  This study is testing a new gel to see if it helps people heal better after skull base surgery compared to regular packing methods.

  Recruiting Indiana University · Indianapolis, Indiana · NCT05898074

• Observational study on managing sinonasal and skull-base tumors

  This study looks at how patients with sinonasal and skull-base tumors are treated and what their experiences are, to help improve care for these conditions.

  Recruiting University Medical Centre Ljubljana · Ljubljana, Ljubljana · NCT05607888

• Assessing complications after skull base tumor surgery

  This study is testing if using lung ultrasound can help find patients at risk for breathing problems and blood clots after surgery for skull base tumors.

  Recruiting Beijing Tiantan Hospital · Beijing · NCT06587906

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.