An anatomical system to guide surgery for placenta accreta

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a prospective cohort study that integrates prenatal ultrasound staging with a structured intraoperative topographic classification to guide surgical decision-making for placenta accreta spectrum. Patients undergo standardized prenatal assessment, real-time intraoperative staging with photos and videos, and then surgical management chosen according to the classification (from cesarean hysterectomy to one-step conservative procedures). The study will collect intraoperative blood loss metrics, correlate surgical findings with pathology, and compare preoperative ultrasound to intraoperative and postoperative data to validate the system. Data collection and follow-up are planned over approximately 36–48 months to assess feasibility, acceptability, and clinical outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Pregnant people suspected of having PAS based on ultrasound findings or clinical risk factors
* Patients undergoing planned surgical intervention for PAS, including a planned cesarean
* Individuals who provide informed consent to participate in the study
* Patients with at least one prenatal assessment before surgery
* Expected age range: 18-55
* Patient has agreed to conservative management approach as part of standard of care if feasible intraoperatively

Exclusion Criteria:

* Patients who decline participation or withdraw consent
* Those with contraindications to the planned surgical procedure

Where it's running

• University of California, Los Angeles
  Los Angeles, California, United States Recruiting

Study contacts

• Principal investigator: Yalda Afshar, MD, PhD — University of California, Los Angeles
• Study coordinator: Dana Levin-Lopez, MPH
• Email: dlevinlopez@mednet.ucla.edu
• Phone: 310-794-8893

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.