ALDH2 gene variations and survival in people with esophageal cancer

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study will genotype ALDH2 variants, focusing on rs671, in patients with pathologically confirmed esophageal cancer and link those variants to clinical survival outcomes. Researchers will use leftover patient samples provided with consent and analyze survival data while accounting for exposures like alcohol and tobacco. The work is motivated by the known effect of the ALDH2*2 allele on acetaldehyde metabolism and its high prevalence in East Asian populations. The study is conducted at National Taiwan University Hospital and excludes female patients and minors.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients who have been pathologically confirmed to have esophageal cancer and who have previously signed consent forms indicating their willingness to provide remaining samples for subsequent studies.

Exclusion Criteria:

* Female patients or patients younger than 18 years old

Where it's running

• National Taiwan University Hospital
  Taipei, Taiwan Recruiting

Study contacts

• Study coordinator: Jang-Ming Lee
• Email: jmlee@ntu.edu.tw
• Phone: +886223123456

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.