Clinical trial Recruiting at 1 site Interventional Ages 18 to 60

Air-polishing versus manual root cleaning during gum recession surgery

Official title: Impact of Root Surface Conditioning With Erythritol Air Polishing Versus Hand Instrumentation on Recession Coverage Using the Modified Tunnel Technique and Subepithelial Connective Tissue Graft: A Randomized Clinical Trial

Run by Medical University of Warsaw · NCT07403006 · Data updated 2026-11-12

We will test if using erythritol air-polishing instead of manual root instrumentation during gum recession surgery helps cover exposed roots in adults with multiple RT1/RT2 recessions.

More Gingival Recession trials

Quick facts

Study typeInterventional
Ages18 Years to 60 Years
SexAll
Enrollment20 (estimated)
SponsorMedical University of Warsaw
Academic / other
Locations1 site (Warsaw, Mazowsze)
StatusRecruiting
StartedMarch 9, 2026
Main results expectedJune 2027
Study endsJuly 2027
Registry record updatedOctober 2, 2026
Trial IDNCT07403006 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults (≥18 years) with multiple symmetric bilateral RT1 or RT2 gingival recessions, good plaque and bleeding scores (<15% FMPS and FMBOP), and a detectable CEJ are ideal candidates.

Probably not a fit

Patients with RT3 recessions, recessions on second or third molars, active periodontitis, uncontrolled systemic conditions affecting healing, or cervical lesions that obscure the CEJ are unlikely to benefit from this protocol.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Adults with multiple symmetrical bilateral RT1 or RT2 gingival recessions and good oral hygiene will undergo recession coverage using a modified tunnel technique with a subepithelial connective tissue graft. Root surfaces on one side will be conditioned with erythritol air-polishing and the contralateral side with standard manual root instrumentation to allow a within-patient comparison. Outcomes will focus on recession coverage and surgical healing to see whether the less invasive air-polishing method yields comparable or better results. The protocol requires detectable cemento-enamel junction and excludes conditions that impair wound healing.

Why it matters

Potential benefit: If successful, using erythritol air-polishing could make root preparation less invasive and reduce tissue trauma while achieving similar or better recession coverage.

How similar studies have gone: Some preliminary clinical and laboratory work supports erythritol air-polishing for biofilm removal, but robust clinical evidence showing superior root coverage outcomes compared with manual instrumentation is limited.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Multiple RT1 and/or RT2 gingival recessions, symmetrical and bilateral, with a minimum height of ≥ 1 mm
* Full-mouth plaque score (FMPS) \< 15% (assessed on four surfaces per tooth)
* Full-mouth bleeding on probing (FMBOP) \< 15% (assessed on four surfaces per tooth)
* Detectable cemento-enamel junction (CEJ)
* Age ≥ 18 years

Exclusion Criteria:

* RT3 gingival recessions
* Gingival recessions affecting second and third molars
* Systemic or infectious diseases that may impair wound healing, including active malignancy, diabetes mellitus with HbA1c \> 7.0%, history of head and neck radiotherapy, true xerostomia, and HIV/AIDS
* Cervical caries, non-carious cervical lesions, or Class V restorations interfering with the CEJ
* Active periodontitis
* Use of medications affecting periodontal tissues or wound healing, including systemic corticosteroids, immunosuppressants, isotretinoin, bisphosphonates, and monoclonal antibodies with immunosuppressive, antiresorptive, or antiangiogenic effects
* Smoking
* Pregnancy or breastfeeding

Where it's running

  • Department of Periodontology and Oral Mucosa Diseases, Medical University of Warsaw, Warsaw
    Warsaw, Mazowsze, Poland
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.