AI versus conventional digital design for dental crowns
Accuracy Assessment of Artificial Intelligence Versus Conventional Digital Design for Fixed Dental Prosthesis: (An Invitro Study)
This project will test whether an AI system can design dental crowns as accurately as conventional CAD software for adults (18–65) who need fixed dental prostheses.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 1000 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Sponsor | October University for Modern Sciences and Arts Academic / other |
| Locations | 1 site (Giza) |
| Trial ID | NCT07432165 on ClinicalTrials.gov |
What this trial studies
This in vitro, comparative study will use 438 high-quality digital intraoral scans to compare AI-generated prosthesis designs with manually created CAD restorations by experienced dental technicians. The AI workflow is trained (60%), validated (10%), and tested (30%) on historical human-designed FDP datasets and natural tooth morphology. Accuracy of the designs will be measured by 3D superimposition and quantified using Intersection over Union (IOU), with margin detection evaluated by F1 score, precision, and recall. Statistical comparisons will use paired t-tests with significance set at P ≤ 0.05.
Who should consider this trial
Good fit: Adults aged 18–65 with a damaged tooth requiring a fixed dental prosthesis and who can provide a high-quality intraoral digital scan are ideal candidates.
Not a fit: Patients with poor or incomplete scans, severe occlusal abnormalities, or those outside the 18–65 age range are unlikely to benefit from this study's results.
Why it matters
Potential benefit: If successful, the AI approach could speed up and standardize crown design, reducing technician workload and turnaround time for prostheses.
How similar studies have performed: Similar AI-assisted CAD/CAM approaches in dentistry have shown promising results in small in vitro and pilot studies, but broad clinical validation is still limited.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults aged 18-65 years Patients with a damaged tooth requiring a fixed dental prosthesis Available digital intraoral scans Adequate occlusal anatomy for analysis of opposing teeth Exclusion Criteria: * Incomplete or poor-quality digital scans Severe occlusal abnormalities affecting analysis Patients outside the specified age range
Where this trial is running
Giza
- MSA University — Giza, Egypt (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.