Clinical trial Recruiting at 1 site Observational Ages 18 and up

AI tool to recognize anatomy and find lesions during nasopharyngolaryngoscopy

Official title: Development and Validation of an Artificial Intelligence System for Anatomic Site Recognition and Lesion Detection Based on Electronic Nasopharyngolaryngoscopic Images: A Prospective Multicenter Study

Run by Ruijin Hospital · NCT07326358 · Data updated 2026-11-12

This project will try an AI system that reads nasopharyngolaryngoscopy images to help doctors spot anatomy and lesions in adults having these exams.

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Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment500 (estimated)
SponsorRuijin Hospital
Academic / other
Locations1 site (Shanghai)
StatusRecruiting
StartedDecember 12, 2025
Main results expectedDecember 31, 2026
Study endsMarch 31, 2027
Registry record updatedJanuary 8, 2026
Trial IDNCT07326358 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults (age 18 or older) who underwent standard electronic nasopharyngolaryngoscopy at the enrolling site and can provide informed consent, with clear images available for use.

Probably not a fit

Patients whose images are of poor quality, have severe motion artifacts, or contain incomplete lesion views are unlikely to benefit from the AI model.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The study will collect standard electronic nasopharyngolaryngoscopy images and basic patient information from adult patients at participating centers to train and validate a deep learning model. Retrospective image and metadata collection, including biopsy-confirmed pathology when available, will be used for model development. After training and internal validation, the model's clinical performance will be tested on an independent, prospectively collected cohort. The aim is to improve anatomic recognition and lesion detection during nasopharyngolaryngoscopy.

Why it matters

Potential benefit: If successful, the AI could reduce missed or misidentified areas on examination and help clinicians detect lesions earlier, potentially improving diagnosis and treatment planning.

How similar studies have gone: Deep learning approaches have shown promise in other endoscopic and laryngoscopic image-detection tasks, but AI specifically applied to nasopharyngolaryngoscopy remains relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age ≥ 18 years;
* Underwent standard electronic nasopharyngolaryngoscopy;
* Patients who underwent biopsy sampling have a clear pathological diagnosis;
* Signed a written informed consent form.

Exclusion Criteria:

* Image quality is substandard with severe motion artifacts;
* Lesion images are unclear and incomplete.

Where it's running

  • Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
    Shanghai, China
    Recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.