AI system for analyzing spinal deformities

AI-Powered Scoliosis Auto-Analysis System Multicenter Development and Validations

The University of Hong Kong · NCT05146193

This study is testing a new AI system that helps doctors better diagnose and understand spinal deformities by analyzing patient images.

Quick facts

Study typeObservational
Enrollment2500 (estimated)
Ages10 Years to 80 Years
SexAll
SponsorThe University of Hong Kong (other)
Locations1 site (Hong Kong)
Trial IDNCT05146193 on ClinicalTrials.gov

What this trial studies

This study aims to develop and validate an AI-powered system called AlignProCARE to assist clinicians in diagnosing and assessing spinal deformities. The approach involves collecting radiographs and nude back images from patients with various spinal conditions across multiple centers in Malaysia, China, and Japan. By automating the landmark placement process, the system seeks to reduce variability and improve the accuracy of spine alignment assessments. The study will also involve follow-up imaging to refine the AI model further.

Who should consider this trial

Good fit: Ideal candidates include adults with idiopathic scoliosis or other spinal deformities such as spondylolisthesis and kyphosis.

Not a fit: Patients who have undergone spinal surgery or refuse imaging will not benefit from this study.

Why it matters

Potential benefit: If successful, this AI system could lead to faster and more accurate diagnoses of spinal deformities, improving treatment planning for patients.

How similar studies have performed: Other studies have shown promise in using AI for medical imaging analysis, indicating potential success for this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Idiopathic scoliosis, adult deformity (spondylolisthesis, idiopathic kyphosis, kyphoscoliosis, lordoscoliosis)

Exclusion Criteria:

* Refusal for imaging, postoperative patients

Where this trial is running

Hong Kong

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Spinal Deformity, Adult deformity, scoliosis, spondylolisthesis

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.