AI-guided early thrombolysis for people with STEMI

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a cluster-randomized interventional program comparing an AI-assisted mobile application to usual care across participating hospitals and regions in China. The app is used to guide timely thrombolysis combined with coordination for PCI in adults presenting with ST-elevation myocardial infarction within 12 hours of symptom onset. The trial enrolls patients for whom guide-wire passage through the culprit lesion is not expected within 120 minutes of diagnosis and aims to increase pre-hospital and early in-hospital thrombolysis. Outcomes include time from symptom onset to reperfusion and clinical endpoints related to myocardial salvage and complications.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* (the following inclusion conditions shall be met at the same time):

  1. age: ≥ 18 years and ≤ 80 years;
  2. Chest pain lasted for more than 30 min, and the onset time of chest pain was ≤ 12 hours;
  3. ECG: ST segment elevation after J-point in 2 or more adjacent leads: limb leads ≥ 0.1 mv or chest leads ≥ 0.2 mv;
  4. it is expected that "guide wire passing through the lesion" could not be achieved within 120 min after the diagnosis of STEMI;
  5. Signed informed consent .

Exclusion Criteria:

* (1) Cardiac rupture; (2) Complete left bundle branch block (LBBB) or ventricular pacing; (3) There are contraindications to thrombolysis; (4) Have serious comorbidities; (5) Have complex heart disease; (6) There are situations that are not suitable for clinical trials.

Where it's running

• No. 83, Wenhua Road, Shenhe District, Shenyang City
  Shenyang, Liaoning, China Recruiting

Study contacts

• Study coordinator: Kai Xu, MD,PhD
• Email: xukai2001@sina.com
• Phone: +8615309880917

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.