AI-designed single tooth dental prostheses

Artificial Intelligence in Prosthodontics - Design of Maxillary Single-tooth Dental Prostheses

Observational The University of Hong Kong · NCT05056948

This study is testing if using artificial intelligence can help create better-fitting single-tooth dental replacements by comparing different computer methods to see which one works best.

Quick facts

Study typeObservational
Enrollment250 (estimated)
Ages18 Years and up
SexAll
SponsorThe University of Hong Kong Academic / other
Locations1 site (Sai Ying Pun)
Trial IDNCT05056948 on ClinicalTrials.gov

What this trial studies

This study aims to explore the use of artificial intelligence in designing single-tooth dental prostheses by analyzing the features of 3D models of existing teeth. It will compare four deep-learning algorithms to determine which method best predicts the occlusal morphology and 3D position of a missing tooth. The study will involve collecting 200 maxillary dentate teeth models for training and 100 models for validation, assessing the need for antagonist models in the design process. The ultimate goal is to improve the efficiency and accuracy of dental prosthesis design.

Who should consider this trial

Good fit: Ideal candidates are Cantonese individuals with sufficient dentition and stable occlusal relationships.

Not a fit: Patients with periodontal disease or significant alterations in tooth morphology will likely not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could lead to more precise and quicker fitting of dental prostheses, enhancing patient satisfaction and quality of life.

How similar studies have performed: While the application of AI in dental prosthesis design is a novel approach, similar studies in other areas of healthcare have shown promising results.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Subjects with sufficient dentition present for the determination of the upper occlusal plane
* Subjects with more than 12 occluding pairs and stable intercuspal position
* Subjects with teeth restorations that did not grossly alter its morphology
* Subjects who did not undergo orthodontic treatment and/or did not have teeth that rotated more than 45 degrees and/or displaced more than 1.5 mm
* Subjects who are of Cantonese descent.

Exclusion Criteria:

* Subjects with periodontal disease whereby there is pathological tooth migration and alteration of occlusal plane.
* Subjects who are under the age of 18 and unable to give consent.
* Subjects with extensive teeth restorations that affect the morphology.

Where this trial is running

Sai Ying Pun

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Dental ProsthesisArtificial IntelligenceMachine LearningDeep Neural NetworkGenerative Adversarial NetworkBiomimeticsDental ProsthesesProsthodontic Treatment
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.