AI-assisted renal biopsy diagnosis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Researchers will collect light microscopy, special stain, immunofluorescence, and transmission electron microscopy images from patients undergoing renal biopsy for chronic glomerulonephritis. An artificial intelligence diagnostic model will analyze these images and its outputs will be compared to the pathologists' gold-standard diagnoses. The study will report performance metrics such as area under the curve (AUC), sensitivity, and specificity. This is an observational comparison of model results versus standard pathological interpretation at two Guangzhou hospitals.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Voluntary signing of informed consent form;
2. Patients clinically diagnosed or suspected of having chronic kidney disease according to the 2023 KDIGO Clinical Practice Guideline for the Evaluation and Management of Kidney Disease;
3. Undergoing renal biopsy and pathological specimen preparation.

Exclusion Criteria:

1. Biopsy tissue from donor kidney or transplanted kidney;
2. Poor quality of pathological specimen, unable to conduct pathological diagnosis.

Where it's running

• Nanfang Hospital
  Guangzhou, Guangdong, China Recruiting
• Zhujiang Hospital of Southern Medical University
  Guangzhou, Guangdong, China Recruiting

Study contacts

• Study coordinator: Yangshu Zhou
• Email: 764709402@qq.com
• Phone: 020-61643888

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.