AI-assisted personalized legacy program — Reflections: My Story
Feasibility and Acceptability of AI Assisted Personalized Legacy Program (Reflections: My Story) for Patients With Serious Illness
This AI-assisted personalized legacy program tries to help adults with serious illness reflect on their life and create a keepsake document to share with loved ones.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 40 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Mayo Clinic Academic / other |
| Locations | 2 sites (Phoenix, Arizona and 1 other locations) |
| Trial ID | NCT07009210 on ClinicalTrials.gov |
What this trial studies
This is a multi-site, minimal-risk pilot conducted at Mayo Clinic to test feasibility and acceptability of a brief, individualized psychotherapy called the AI Assisted Personalized Legacy Program. Patients meet with a trained facilitator to reflect on life memories and values while sessions are recorded and transcribed. The interventionist and patient work together to edit the transcript into a polished legacy document that the patient can keep and share. The pilot will document recruitment, delivery, participant feedback, and preliminary signals of emotional or existential benefit.
Who should consider this trial
Good fit: Adults (age ≥18) with a serious illness who are English-fluent, can provide informed consent, and can complete questionnaires with or without assistance are the intended participants.
Not a fit: Patients with active delirium, advanced dementia, untreated severe psychiatric disorders (such as untreated schizophrenia or bipolar disorder), recent psychiatric hospitalization, or those already receiving concurrent legacy services are unlikely to benefit or be eligible.
Why it matters
Potential benefit: If successful, the program could reduce existential and psycho-emotional distress and improve patient and family experience by producing a meaningful, shareable legacy document.
How similar studies have performed: Non-AI life-review and legacy interventions in palliative care have shown promising reductions in existential distress and improved family satisfaction, but AI-assisted personalized legacy programs are relatively novel and less well tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Participant population: Adults with serious illness - defined as a health condition that carries a high risk of mortality Inclusion Criteria for patients: 1. Age ≥18 years 2. English fluency 3. Provide informed consent 4. Ability to complete questionnaire(s) by themselves or with assistance Exclusion Criteria: 1. Other psychological co-morbidities such as untreated schizophrenia, bipolar disease 2. Recent suicide attempt or psychiatric illness severe enough that hospitalization has been necessary in last 6 months 3. Active delirium 4. Advanced dementia 5. Participation in concurrent legacy offerings through the palliative care clinic
Where this trial is running
Phoenix, Arizona and 1 other locations
- Mayo Clinic — Phoenix, Arizona, United States (Recruiting)
- Mayo Clinic — Rochester, Minnesota, United States (Recruiting)
Study contacts
- Principal investigator: Deirdre Pachman, MD — Mayo Clinic
- Study coordinator: Melissa Felt
- Email: felt.melissa@mayo.edu
- Phone: 507-255-4162
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.