AI-assisted EGGIM scoring for gastric intestinal metaplasia
Artificial Intelligence in Assessing Gastric Intestinal Metaplasia Via the EGGIM Score
Qilu Hospital of Shandong University · NCT07257796
This study tests if an AI tool can automatically calculate EGGIM scores from endoscopy images to measure gastric intestinal metaplasia in adults undergoing image-enhanced endoscopy.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 3000 (estimated) |
| Ages | 40 Years to 75 Years |
| Sex | All |
| Sponsor | Qilu Hospital of Shandong University (other) |
| Locations | 3 sites (Jinan, Shandong and 2 other locations) |
| Trial ID | NCT07257796 on ClinicalTrials.gov |
What this trial studies
This is a prospective, multicenter validation of an artificial intelligence system that automatically reads endoscopic images and generates EGGIM scores for gastric intestinal metaplasia. Adults aged 40–75 undergoing image-enhanced endoscopy at three hospitals in Jinan will be enrolled after informed consent. The AI-generated scores will be compared with endoscopists' readings and, where available, histology to measure accuracy, consistency, and reliability. The protocol expands on preliminary pilot data from a prior investigation (NCT05464108).
Who should consider this trial
Good fit: Adults 40–75 years old who are undergoing image-enhanced endoscopy (IEE) and can give informed consent, without prior gastric surgery and without severe organ dysfunction, are the ideal candidates.
Not a fit: People outside the 40–75 age range, unable to undergo gastroscopy or IEE, with prior stomach surgery, or with severe cardiac, cerebral, pulmonary, renal, or psychiatric disorders are unlikely to benefit.
Why it matters
Potential benefit: If successful, the AI could make EGGIM scoring faster and more consistent, helping clinicians detect precancerous gastric changes earlier.
How similar studies have performed: Previous pilot work (NCT05464108) and other AI applications in endoscopy have shown promise, but this larger multicenter validation is needed to confirm performance.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * patients aged 40-75 years who undergo the IEE examination * patients who voluntarily sign the informed consent form Exclusion Criteria: * patients with severe cardiac, cerebral, pulmonary or renal dysfunction or psychiatric disorders who cannot participate in gastroscopy * patients with previous surgical procedures on the stomach
Where this trial is running
Jinan, Shandong and 2 other locations
- Qilu Hospital of Shandong University — Jinan, Shandong, China (RECRUITING)
- Shandong First Medical University First Affiliated Hospital — Jinan, Shandong, China (NOT_YET_RECRUITING)
- Shandong Second Provincial General Hospital — Jinan, Shandong, China (NOT_YET_RECRUITING)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Intestinal Metaplasia of Gastric Mucosa, Artificial Intelligence, Endoscopy