Aerobic versus resistance exercise during hemodialysis to change the atherogenic index
Official title: Aerobic Versus Resistive Intradialytic Training Effect on Atherogeinc Index in Hemodialysis Patients
Run by Cairo University · NCT07045064 · Data updated 2026-11-12
This trial will test whether doing aerobic or resistance exercise during dialysis can change the atherogenic index in adults on maintenance hemodialysis aged 40–60.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 40 Years to 60 Years |
| Sex | All |
| Enrollment | 60 (estimated) |
| Sponsor | Cairo University Academic / other |
| Locations | 2 sites (Cairo, Select State and 1 other locations) |
| Status | Recruiting |
| Started | July 4, 2025 |
| Main results expected | January 2026 |
| Study ends | March 2026 |
| Registry record updated | July 9, 2025 |
| Trial ID | NCT07045064 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults 40–60 years old on maintenance hemodialysis three times weekly for at least three months with BMI 18.5–29.9 kg/m² and no major unstable cardiac, infectious, malignant, or neurologic conditions.
✕Probably not a fit
Patients with unstable angina, heart failure, uncontrolled hypertension, severe infection, malignant tumors, or significant neurologic disease are unlikely to benefit and are excluded for safety reasons.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This randomized controlled trial will enroll 60 men and women aged 40–60 who have been on maintenance hemodialysis at least three months. Participants will be randomly assigned to one of three groups: intradialytic aerobic exercise, intradialytic resistive exercise, or a usual-care control group. Interventions are performed during regular dialysis sessions three times per week and the primary outcome is change in atherogenic index, with standard safety monitoring and exclusion of patients with unstable cardiovascular or severe systemic disease. The trial is conducted at the National Institute of Kidney and Urology, Mataria, under Cairo University oversight and informed consent and local ethics approvals are required.
Why it matters
Potential benefit: If successful, the interventions could lower atherogenic markers and potentially reduce cardiovascular risk in people on hemodialysis.
How similar studies have gone: Prior intradialytic exercise studies have shown improved fitness and some favorable changes in cardiovascular risk markers, but effects specifically on the atherogenic index are less well established.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: .Maintenance hemodialysis ≥ 3 months. .BMI will be ranged from 18.5 to 29.9 kg/m². .Age ≥ 40years and ≤ 60 years. .Hemodialysis 3 times a week. Exclusion Criteria: .patients suffered from any central and peripheral nervous system diseases. .patients suffered from serious complications, such as heart failure, severe infection and malignant tumor. .uncontrolled hypertension with systolic blood pressure ⩾200 mm Hg and/or diastolic blood pressure ⩾120 mm Hg. .unstable angina
Where it's running
-
National Institute of Kidney and Urology, Mataria
Cairo, Egypt Recruiting -
National Institute of Kidney and Urology, Mataria
Cairo, Select State, Egypt Not yet recruiting
Study contacts
- Study coordinator: mariam rezk rezk, lecturer assistant
- Email: mariam.rezk112003@gmail.com
- Phone: 01280207863
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.