Advanced ultrasound protocols for arm, kidney, and brain blood vessels
Unlock the Power of Resona 9 Ultrasound Machine: an Observational Study to Set-up and Test New Advanced Vascular Imaging Protocols
This will test new advanced ultrasound scans of arm, kidney, and brain blood vessels in adults without prior kidney or brain disease to create reference values and check measurement repeatability.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 60 (estimated) |
| Ages | 18 Years to 75 Years |
| Sex | All |
| Sponsor | Mario Negri Institute for Pharmacological Research Academic / other |
| Locations | 1 site (Ranica, BG) |
| Trial ID | NCT06841887 on ClinicalTrials.gov |
What this trial studies
This single-center observational project will perform ultrasound examinations using the new Resona 9 system on 60 adult volunteers at the Mario Negri Institute's Clinical Research Centre in Ranica, Italy. Participants aged 18–75 with no history of kidney or cerebral disease will undergo standardized ultrasound acquisitions of arm, cerebral, and renal vascular territories and may be asked to return for repeat exams to test reproducibility. The primary aim is to set up and test advanced ultrasound imaging protocols, while secondary objectives include defining normal reference ranges, evaluating repeatability and reproducibility of measurements, and examining correlations with age and sex. Quantitative image processing will be used to identify potential imaging biomarkers and inform future diagnostic or monitoring applications.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18–75 who can give informed consent and have no prior kidney, cerebral, or other vascular-impacting diseases.
Not a fit: People with a history of kidney or cerebral disease, or those unable to consent or cooperate, are unlikely to benefit from participation.
Why it matters
Potential benefit: If successful, the project could provide more reproducible, high-resolution noninvasive imaging protocols and reference values to improve detection and monitoring of vascular changes in renal and cerebral conditions.
How similar studies have performed: Previous ultrasound and imaging-biomarker research supports the feasibility of noninvasive vascular measurements, but these specific Resona 9–based advanced protocols and the planned reference-value set are largely novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Provision of informed consent prior to any study specific procedures * Female and/or male aged between 18 and 75 years * No previous history of kidney or cerebral disease and no pathologies that might have affected the vascular system Exclusion Criteria: * Previous history of kidney or cerebral disease or pathologies that might have affected the vascular system * Legal incapacity, limited legal capacity, intellectual disability, uncooperative attitude or any other evidence that the subject will not be able to understand the study aims and procedures
Where this trial is running
Ranica, BG
- Clinical Research Centre for Rare Diseases Aldo e Cele Daccò — Ranica, Bg, Italy (Recruiting)
Study contacts
- Study coordinator: Michela Bozzetto, Ph.D.
- Email: michela.bozzetto@marionegri.it
- Phone: +39 035 4535 381
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.