Advanced ultrasound protocols for arm, kidney, and brain blood vessels
Official title: Unlock the Power of Resona 9 Ultrasound Machine: an Observational Study to Set-up and Test New Advanced Vascular Imaging Protocols
Run by Mario Negri Institute for Pharmacological Research · NCT06841887 · Data updated 2026-11-12
This will test new advanced ultrasound scans of arm, kidney, and brain blood vessels in adults without prior kidney or brain disease to create reference values and check measurement repeatability.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 75 Years |
| Sex | All |
| Enrollment | 60 (estimated) |
| Sponsor | Mario Negri Institute for Pharmacological Research Academic / other |
| Locations | 1 site (Ranica, BG) |
| Status | Recruiting |
| Started | May 9, 2025 |
| Main results expected | March 2027 |
| Study ends | March 2027 |
| Registry record updated | September 5, 2025 |
| Trial ID | NCT06841887 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 18–75 who can give informed consent and have no prior kidney, cerebral, or other vascular-impacting diseases.
✕Probably not a fit
People with a history of kidney or cerebral disease, or those unable to consent or cooperate, are unlikely to benefit from participation.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This single-center observational project will perform ultrasound examinations using the new Resona 9 system on 60 adult volunteers at the Mario Negri Institute's Clinical Research Centre in Ranica, Italy. Participants aged 18–75 with no history of kidney or cerebral disease will undergo standardized ultrasound acquisitions of arm, cerebral, and renal vascular territories and may be asked to return for repeat exams to test reproducibility. The primary aim is to set up and test advanced ultrasound imaging protocols, while secondary objectives include defining normal reference ranges, evaluating repeatability and reproducibility of measurements, and examining correlations with age and sex. Quantitative image processing will be used to identify potential imaging biomarkers and inform future diagnostic or monitoring applications.
Why it matters
Potential benefit: If successful, the project could provide more reproducible, high-resolution noninvasive imaging protocols and reference values to improve detection and monitoring of vascular changes in renal and cerebral conditions.
How similar studies have gone: Previous ultrasound and imaging-biomarker research supports the feasibility of noninvasive vascular measurements, but these specific Resona 9–based advanced protocols and the planned reference-value set are largely novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Provision of informed consent prior to any study specific procedures * Female and/or male aged between 18 and 75 years * No previous history of kidney or cerebral disease and no pathologies that might have affected the vascular system Exclusion Criteria: * Previous history of kidney or cerebral disease or pathologies that might have affected the vascular system * Legal incapacity, limited legal capacity, intellectual disability, uncooperative attitude or any other evidence that the subject will not be able to understand the study aims and procedures
Where it's running
-
Clinical Research Centre for Rare Diseases Aldo e Cele Daccò
Ranica, Bg, Italy Recruiting
Study contacts
- Study coordinator: Michela Bozzetto, Ph.D.
- Email: michela.bozzetto@marionegri.it
- Phone: +39 035 4535 381
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.