Advanced imaging techniques for eye diseases

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study explores the use of innovative imaging technologies, specifically Optical Transmission Tomography (OTT), alongside Optical Coherence Tomography (OCT) and Specular Microscopy (SM), to enhance the examination of ocular diseases. Healthy subjects and patients with ocular disorders will undergo imaging sessions at baseline and follow-up visits over a period of up to four years. The goal is to improve the resolution and speed of ocular imaging, which may lead to better understanding and management of conditions like glaucoma and cataracts.

Why it matters

Who can join: the full rules

Inclusion Criteria:

For Patients:

* 200 subjects aged 18 to 80 years;
* Male or female;
* with an ocular disease affecting the cornea, ocular surface, lens (cataract) or glaucoma, or requiring refractive surgery or post-refractive surgery follow-up;
* Are covered by the French Assurance Maladie;
* Have signed an express, free and informed consent form.

For Healthy volunteers:

* 100 subjects aged 18 to 80 years;
* Male or female;
* Healthy subjects with no known pathology directly or indirectly affecting ocular structures;
* Covered by the French Assurance Maladie.
* Having signed an express, free and informed consent form.

Exclusion Criteria:

For all participants:

* Inability to hold a still position on a standard ophthalmic chin rest;
* Conjunctivitis or other contagious contact disease in active phase;
* Having an implanted pacemaker or other electronic medical device;
* Having a predisposition to iridocorneal angle closure;
* Vulnerable persons or persons under legal protection (pregnant or breast-feeding women; persons under guardianship,

Where it's running

• Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts
  Paris, France Recruiting

Study contacts

• Principal investigator: Nacim BOUHERAOUA, PU-PH — Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts
• Study coordinator: Nabil BROUK
• Email: nbrouk@15-20.fr
• Phone: 00 33 1 40 02 11 44

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.