Advanced imaging techniques for diagnosing joint diseases
Official title: Novel Complex Radiodiagnostics of Peripherial Arthropathies
Run by Semmelweis University · NCT05657847 · Data updated 2026-11-12
This study is testing a new type of imaging called photon-counting CT to see if it can better diagnose joint diseases like rheumatoid arthritis compared to traditional methods like MRI and X-rays.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 100 Years |
| Sex | All |
| Enrollment | 500 (estimated) |
| Sponsor | Semmelweis University Academic / other |
| Drugs / interventions | radiation |
| Locations | 3 sites (Budapest and 2 other locations) |
| Status | Recruiting |
| Started | March 7, 2022 |
| Main results expected | February 1, 2027 |
| Study ends | February 1, 2027 |
| Registry record updated | December 20, 2022 |
| Trial ID | NCT05657847 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include individuals diagnosed with rheumatoid arthritis, psoriatic arthritis, or crystal arthropathies who can provide informed consent.
✕Probably not a fit
Patients under 18 or over 100 years old, as well as pregnant or breastfeeding individuals, may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to evaluate the effectiveness of photon-counting detector computed tomography (PCD-CT) in diagnosing chronic peripheral arthritides, including rheumatoid arthritis, psoriatic arthritis, and crystal arthropathies. The study will compare PCD-CT's capabilities against conventional imaging methods like MRI and radiography, focusing on its ability to detect bone erosions, synovitis, and other joint-related abnormalities. Participants will undergo imaging procedures to assess the advantages of PCD-CT, such as improved resolution and lower radiation exposure.
Why it matters
Potential benefit: If successful, this study could lead to more accurate and earlier diagnoses of various forms of arthritis, improving patient outcomes.
How similar studies have gone: While the use of advanced imaging techniques is growing, the specific application of photon-counting detector CT for these conditions is relatively novel and has not been extensively tested in prior studies.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Rheumatoid arthritis (EULAR/ACR Criteria) / Psoriatic arthritis (CASPAR Criteria)/ Crystal arthropathies * signed informed consent Exclusion Criteria: * age: \<18 years, \> 100 years * pregnant * breastfeeding
Where it's running
-
National Institute of Rheumatology and Physiotherapy
Budapest, Hungary Recruiting -
Buda Hospital of the Hospitaller Order of Saint John of God
Budapest, Hungary Recruiting -
Semmelweis University
Budapest, Hungary Recruiting
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.