Advanced brain imaging using EEG and MEG technology
Official title: Development of Electroencephalography (EEG) and Magnetoencephalography (MEG) Source Reconstruction With Fast Multipole Method
Run by Worcester Polytechnic Institute · NCT06471244 · Data updated 2026-11-12
This study is testing a new brain imaging technology that uses a special cap and software to see if it can accurately track brain activity while people do tasks like tapping their fingers or speaking.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 65 Years |
| Sex | All |
| Enrollment | 30 (estimated) |
| Sponsor | Worcester Polytechnic Institute Academic / other |
| Locations | 2 sites (Ilmenau and 1 other locations) |
| Status | Recruiting |
| Started | January 1, 2025 |
| Main results expected | April 1, 2027 |
| Study ends | April 1, 2027 |
| Registry record updated | May 28, 2025 |
| Trial ID | NCT06471244 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are healthy adults aged 18 to 65 with normal hearing and vision who can provide informed consent.
✕Probably not a fit
Patients with neurological or psychiatric conditions, implanted medical devices, or significant claustrophobia may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial aims to evaluate the effectiveness of a new 256 dry electrode EEG cap combined with MEG readings and advanced brain modeling software for real-time source localization of brain activity. Participants will undergo MRI scans to create detailed brain models and will perform tasks such as finger tapping, median nerve stimulation, and speech processing while their brain activity is recorded. The study will compare the predicted locations of brain activity with actual MEG data and known anatomical locations to assess the accuracy of the new technology.
Why it matters
Potential benefit: If successful, this study could enhance the precision of brain activity localization, improving diagnostic and therapeutic approaches for neurological conditions.
How similar studies have gone: While the approach is innovative, similar studies have shown promise in improving brain imaging techniques, suggesting potential for success.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age at least 18 and less than 66 years * Normal hearing and (corrected) vision * Able to understand and give informed consent Exclusion Criteria: * Cardiac pacemaker or pacemaker wires; neurostimulators; implanted pumps * Metal in the body (rods, plates, screws, shrapnel, dentures, IUD) or metallic particles in the eye * Surgical clips in the head or previous neurosurgery * Any magnetic particles in the body * Cochlear implants * Prosthetic heart valves * History of skull injury or defects * Significant claustrophobia; Ménière's disease * Pregnancy, breast feeding * Neurological or psychiatric diagnoses or medications influencing brain function * Current substance abuse (exception: concurrent nicotine use is allowed) * Failure to perform the behavioral tasks or psychological evaluation tests * Prisoners
Where it's running
-
Technical University Ilmenau
Ilmenau, Germany Recruiting -
Max-Planck-Institut für Kognitions- und Neurowissenschaften [Cognitive and Neuroscience]
Leipzig, Germany Recruiting
Study contacts
- Principal investigator: Sergey N Makaroff, PhD — Worcester Polytechnic Institute
- Study coordinator: Sergey N Makaroff, PhD
- Email: snmakaroff@wpi.edu
- Phone: 508-831-5017
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.