Adults' views of childhood toxin injections for cerebral palsy
Official title: How Do Adults With Cerebral Palsy Perceive Their Botulinum Toxin Treatment During Childhood ?
Run by Centre Médico-Chirurgical de Réadaptation des Massues Croix Rouge Française · NCT07377201 · Data updated 2026-11-12
This survey asks adults with cerebral palsy who had repeated botulinum toxin injections as children to report how those treatments affected them long term.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 500 (estimated) |
| Sponsor | Centre Médico-Chirurgical de Réadaptation des Massues Croix Rouge Française Academic / other |
| Locations | 1 site (Lyon) |
| Status | Recruiting |
| Started | February 1, 2026 |
| Main results expected | August 1, 2027 |
| Study ends | August 1, 2027 |
| Registry record updated | September 9, 2026 |
| Trial ID | NCT07377201 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults (age ≥18) with a diagnosis of cerebral palsy who received more than two series of botulinum toxin injections during childhood and can complete the questionnaire are ideal candidates.
✕Probably not a fit
People who never had repeated childhood toxin injections or who cannot complete the questionnaire or provide the required confirmation information are unlikely to benefit from this survey.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational project uses a patient-reported questionnaire to collect adult perspectives on repeated childhood botulinum toxin injections and other pediatric interventions for cerebral palsy. Eligible participants are 18 or older, have a CP diagnosis, received more than two series of toxin injections in childhood, and can complete the survey (with assistance if needed). The questionnaire captures functional, emotional, and satisfaction-related outcomes across all GMFCS levels. Results aim to fill gaps in long-term, patient-centered outcome data to inform future care decisions.
Why it matters
Potential benefit: If successful, the survey could clarify how childhood toxin injections influence long-term satisfaction and quality of life, helping clinicians align pediatric spasticity care with patient values.
How similar studies have gone: Some prior research has examined long-term clinical outcomes of botulinum toxin in CP, but long-term patient-reported perspectives on repeated childhood injections remain limited, making this survey relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Participants aged 18 years or older * Diagnosed with cerebral palsy * Received repeated toxin injections during childhood (\> 2 series of injections) * Agreeing to complete the questionnaire * Possessing sufficient cognitive abilities, particularly in terms of reading comprehension and oral comprehension (even if someone had to physically assist them in responding) * All levels of the GMFCS classification 1 to 5 Exclusion Criteria: * Individuals who do not meet the above criteria, as confirmed by the statements in Part 1 of the survey, will be automatically excluded from the study.
Where it's running
-
CMCR des Massues
Lyon, France Recruiting
Study contacts
- Study coordinator: Dr Emmanuelle Chaleat-Valayer
- Email: emmanuelle.chaleat-valayer@croix-rouge.fr
- Phone: +33 4 72 38 48 58
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Manual Therapy Before Neuromotor Rehab in Children with Cerebral Palsy
In this pilot study, researchers test whether 30 minutes of lower-limb manual therapy before functional neuromotor therapy helps improve gait and motor performance in children with spastic cerebral palsy.
-
Co-designed wrist-hand orthosis for children with neuromotor disorders
In children aged 6 to 14 with neuromotor conditions after brain injury, researchers are testing a wrist-hand brace designed with input from the kids to see if it fits better and is easier to use than their current orthosis.
-
Outcomes of tone-management surgery in children with spastic/dystonic quadriplegia
This study tests how well intrathecal baclofen pumps and dorsal/ventral rhizotomy help improve movement, comfort, and daily life for kids with severe CP and high muscle tone.
-
Wearable eye tracking during bimanual tasks in children with cerebral palsy
This study tests whether wearable eye-tracking glasses can reliably record eye movements while children with CP and typically developing peers perform two-handed tasks.
-
Able Kids device: safer gait aid for kids with neurologic gait problems
This study tests whether the ABLE Kids wearable exoskeleton can be safely used during a 10-session gait training program for children with neurological gait disorders or muscle weakness.
-
Dorsal Root Electrical Stimulation to Help Spasticity in Children with Cerebral Palsy
This study tests whether adding dorsal root electrical stimulation during SDR surgery can lessen spasticity in children with cerebral palsy.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.