Adults' views of childhood toxin injections for cerebral palsy
How Do Adults With Cerebral Palsy Perceive Their Botulinum Toxin Treatment During Childhood ?
This survey asks adults with cerebral palsy who had repeated botulinum toxin injections as children to report how those treatments affected them long term.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 500 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Centre Médico-Chirurgical de Réadaptation des Massues Croix Rouge Française Academic / other |
| Locations | 1 site (Lyon) |
| Trial ID | NCT07377201 on ClinicalTrials.gov |
What this trial studies
This observational project uses a patient-reported questionnaire to collect adult perspectives on repeated childhood botulinum toxin injections and other pediatric interventions for cerebral palsy. Eligible participants are 18 or older, have a CP diagnosis, received more than two series of toxin injections in childhood, and can complete the survey (with assistance if needed). The questionnaire captures functional, emotional, and satisfaction-related outcomes across all GMFCS levels. Results aim to fill gaps in long-term, patient-centered outcome data to inform future care decisions.
Who should consider this trial
Good fit: Adults (age ≥18) with a diagnosis of cerebral palsy who received more than two series of botulinum toxin injections during childhood and can complete the questionnaire are ideal candidates.
Not a fit: People who never had repeated childhood toxin injections or who cannot complete the questionnaire or provide the required confirmation information are unlikely to benefit from this survey.
Why it matters
Potential benefit: If successful, the survey could clarify how childhood toxin injections influence long-term satisfaction and quality of life, helping clinicians align pediatric spasticity care with patient values.
How similar studies have performed: Some prior research has examined long-term clinical outcomes of botulinum toxin in CP, but long-term patient-reported perspectives on repeated childhood injections remain limited, making this survey relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Participants aged 18 years or older * Diagnosed with cerebral palsy * Received repeated toxin injections during childhood (\> 2 series of injections) * Agreeing to complete the questionnaire * Possessing sufficient cognitive abilities, particularly in terms of reading comprehension and oral comprehension (even if someone had to physically assist them in responding) * All levels of the GMFCS classification 1 to 5 Exclusion Criteria: * Individuals who do not meet the above criteria, as confirmed by the statements in Part 1 of the survey, will be automatically excluded from the study.
Where this trial is running
Lyon
- CMCR des Massues — Lyon, France (Recruiting)
Study contacts
- Study coordinator: Dr Emmanuelle Chaleat-Valayer
- Email: emmanuelle.chaleat-valayer@croix-rouge.fr
- Phone: +33 4 72 38 48 58
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.