Adjusting gas flow during heart surgery rewarming

Re-Adjustment of Sweep Gas Flow to the During the Rewarming Period of the Cardiopulmonary Bypass to Prevent Alkalosis

Observational Acıbadem Atunizade Hospital · NCT06013189

This study is testing the best way to adjust gas flow during heart surgery to help patients avoid complications as they warm up after surgery.

Quick facts

Study typeObservational
Enrollment90 (estimated)
Ages18 Years and up
SexAll
SponsorAcıbadem Atunizade Hospital Academic / other
Locations1 site (Istanbul, Altunizade)
Trial IDNCT06013189 on ClinicalTrials.gov

What this trial studies

This observational study aims to determine the optimal sweep gas flow during the rewarming phase of cardiopulmonary bypass (CPB) to prevent alkalosis caused by decreased CO2 solubility as temperature increases. By adjusting the sweep gas flow, the study seeks to identify the best practices for managing gas flow during this critical period. The study will involve patients undergoing elective CPB surgery and will monitor the effects of these adjustments on patient outcomes.

Who should consider this trial

Good fit: Ideal candidates for this study are adults over 18 years old scheduled for elective cardiopulmonary bypass surgery.

Not a fit: Patients undergoing minimally invasive surgery, robotic cardiac surgery, deep hypothermia, total circulatory arrest, or those with high FiO2 requirements may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could enhance patient safety and outcomes during heart surgeries involving cardiopulmonary bypass.

How similar studies have performed: While the specific approach of adjusting sweep gas flow during rewarming is novel, similar studies have explored gas management during CPB with varying degrees of success.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients over 18 years of age
* Elective CPB surgery

Exclusion Criteria:

* Patients undergoing minimally invasive surgery
* Patients undergoing robotic cardiac surgery,
* Patients undergoing deep hypothermia,
* Patients undergoing total circulatory arrest,
* Patients whose FiO2 requirement is high that cannot be applied to target gas flow

Where this trial is running

Istanbul, Altunizade

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Optimal Sweep Gas FlowDetermination of Optimal Sweep Gas Flow for Different Phases of Cardiopulmonary Bypasssweep gas flowrewarmingcardiopulmonary bypassalkalosis
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.